Sökning: "triglyceride-rich lipoproteins"

Visar resultat 1 - 5 av 22 avhandlingar innehållade orden triglyceride-rich lipoproteins.

  1. 1. Interaction of Triglyceride-rich Lipoproteins with Platelets and Vitamin K-dependent Coagulation Factors

    Författare :Ning Xu; Avdelningen för klinisk kemi och farmakologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Triglycerides.; Prothrombin; Protein S; Protein C; Platelets; Phospholipids; Metabolism; Lipoproteins; Lipids; Endocytosis; Electron microscopy; Cytochemistry; Coronary heart disease; Blood coagulation factors; Arachidonic acid; Atherosclerosis; Clinical chemistry; Klinisk kemi; Haematology; extracellular fluids; Hematologi; extracellulära vätskor;

    Sammanfattning : 1. During incubation of platelets with 3H-arachidonic acid (20:4, n-6) and 14C-cholesterol doubly labelled and colloidal gold labelled chylomicrons (CMs) and chylomicron remnants (CMRs) CMs were taken up more efficiently than CMRs. Addition of unlabelled CMs, VLDLs, LDLs and HDLs decreased the uptake of labelled CMs. LÄS MER

  3. 2. Triglyceride-rich lipoproteins : postprandial metabolism and composition in relation to atherosclerosis

    Författare :Johan Björkegren; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :triglyceride-rich lipoproteins; very low density lipoproteins; chylomicrons; lipoprotein remnants; apolipoprotein E and C; cholesterol; atherosclerosis;

    Sammanfattning : A relationship between postprandial lipaemia and coronary heart disease (CHD) was established as early as the 1950s. Since then, most attention has been paid to postprandial triglyceride-rich lipoproteins (TRLs) of intestinal origin, i.e. chylomicrons and chylomicron remnants, whereas TRLs of hepatic origin, i. LÄS MER

  4. 3. Lipoproteins in the postprandial state: Studies on the metabolism of triglyceride-rich lipoproteins using multicompartmental models

    Författare :Elias Björnson; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Lipoprotein metabolism; Atherosclerotic cardiovascular disease;

    Sammanfattning : Lipoproteins are lipid-containing spherical particles that circulate in the human blood stream. The reason for their intense study over the decades is their ability to cause atherosclerosis1. LÄS MER

  5. 4. Early perturbations in lipid metabolism in insulin resistance

    Författare :Else Hellebö Johanson; Göteborgs universitet; []
    Nyckelord :insulin resistance; nateglinide; peak VO2; postprandial; relatives; triglyceride-rich lipoproteins; visceral fat; VLDL;

    Sammanfattning : Subjects with the Metabolic Syndrome with or without type 2 diabetes are at excess risk for developing cardiovascular disease. The mechanisms are still not completely understood. Resistance to insulin-stimulated glucose uptake is associated with several metabolic and hemostatic risk factors for cardiovascular disease. LÄS MER

  7. 5. Regulation of plasminogen activator inhibitor-1 : role of triglyceride-rich lipoproteins, fatty acids and fibrate compounds

    Författare :Lennart Nilsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :plasminogen activator inhibitor-1; coronary heart disease; endothelial cells; very low density lipoprotein VLDL ; 4G 5G polymorphism; VLDL response element; fibrate compounds; VLDL receptor; stroke;

    Sammanfattning : Impaired fibrinolytic function secondary to elevated plasma plasminogen activator inhibitor-1 (PAI-1) activity is associated with atherothrombotic disease, in particular coronary heart disease. Both environmental and genetic factors contribute to determine plasma PAI-1 levels and PAI-1 production in vivo. LÄS MER