Sökning: "transverse relaxation"
Visar resultat 1 - 5 av 28 avhandlingar innehållade orden transverse relaxation.
1. Theory of water-proton spin relaxation in complex biological systems
Sammanfattning : In complex biological systems (e.g. gels, cross-linked proteins and biological tissues), the longitudinal spin relaxation of water protons is primarily induced by exchange-mediated orientational randomization (EMOR) of intra- and intermolecular magnetic dipole-dipole couplings. LÄS MER
2. Pushing diffusion MRI towards new dimensions
Sammanfattning : Diffusion-MRI techniques allow the non-invasive investigation of microstructural changes in living tissues. However, a detailed interpretation of the data is complicated by the fact that multiple microscopic environments with varying diffusion properties all contribute to the measured signal. LÄS MER
3. Degradation, Metabolism and Relaxation Properties of Iron Oxide Particles for Magnetic Resonance Imaging
Sammanfattning : Whereas the effect of size and coating material on the pharmacokinetics and biodistribution of iron oxide based contrast agents are well documented, the effect of these parameters on liver metabolism has never been investigated. The primary purpose of this work was to evaluate the effect of iron oxide particle size and coating on the rate of liver clearance and particle degradation using a rat model. LÄS MER
4. Molecular dynamics studied by NMR relaxation experiments. Characterization of functional dynamics in the FK506 binding protein FKBP12
Sammanfattning : The presented thesis work is concerned with the study of molecular dynamics using liquid nuclear magnetic resonance (NMR) spectroscopy. Spin relaxation dispersion experiments in the rotating frame (R1ρ) are employed to provide a detailed, atomic-resolution view of protein dynamics. LÄS MER
5. Proton Relaxation Properties of a Particulate Iron Oxide MR Contrast Agent in Different Tissue Systems : Implications for Imaging
Sammanfattning : Knowledge of the relationship between in vivo contrast agent concentration and magnetic resonance (MR) signal response is an important requirement in contrast enhanced MR imaging in general and in MR based perfusion imaging in particular. This relationship is a complex function of the properties of the contrast agent as well as the structure of the target tissue. LÄS MER