Sökning: "transposable element"

Visar resultat 1 - 5 av 14 avhandlingar innehållade orden transposable element.

  1. 1. Transposable Elements in Neural Progenitor Cells

    Författare :Liana Fasching; Molekylär neurogenetik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Transposable Elements; TRIM28; Epigenetic Regulation; Gene Expression; Neural Progenitor Cells;

    Sammanfattning : More than 90% of DNA does not code for proteins and for a long time these sequences were referred to as “junk DNA” due to their unknown purpose. With the advent of new technologies it is now known, that the non-coding part of the genome is of great importance for regulating gene expression and is therefore indispensable. LÄS MER

  3. 2. Cis-regulatory variation and divergence in Capsella

    Författare :Kim A. Steige; Tanja Slotte; Jeff J. Doyle; Uppsala universitet; []
    Nyckelord :Capsella; Shepherd s Purse; cis-regulatory changes; allele-specific expression; mating system shift; floral evolution; polyploidy; positive selection; purifying selection; transposable elements; small RNA; methylation; transposable element silencing; distribution of fitness effects;

    Sammanfattning : Cis-regulatory changes in e.g. promoters or enhancers that affect the expression of a linked focal gene have long been thought to be important for adaptation. In this thesis, I investigate the selective importance and genomic correlates of cis-regulatory variation and divergence in the genus Capsella, using massively parallel sequencing data. LÄS MER

  4. 3. DNA in centromeres of Chironomus pallidivittatus

    Författare :Ching Liao; Biologiska institutionen; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Genetics; Chironomus; CEN DNA; transposable element; centromere; repetitive DNA; cytogenetics; Genetik; cytogenetik;

    Sammanfattning : The centromeres of most higher eukaryotes are embedded within large regions of constitutive heterochromatin and consist of large quantities of highly repetitive DNA. Transposable elements are also found in these regions. LÄS MER

  5. 4. Organization of centromere associated DNA in Chironomus pallidivittatus

    Författare :Hong He; Biologiska institutionen; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Genetics; Chironomus.; pericentric DNA; repetitive DNA; centromere; transposable element; cytogenetics; Genetik; cytogenetik;

    Sammanfattning : Centromeres have not yet been functionally defined in higher eu- karyotes, largely due to the huge amounts of repeated DNA in these regions of most species and difficulties of delimiting centromeric from pericentric regions. Also the latter have large quantities of mostly noncoding DNA, expressed cytologically as pericentric heterochromatin. LÄS MER

  7. 5. Evolutionary genomics in Corvids : – From single nucleotides to structural variants

    Författare :Matthias H. Weissensteiner; Jochen B.W. Wolf; Manfred Grabherr; Kateryna M. Makova; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; evolutionary genetics; genomics; population genetics; selection; recombination; chromosomal features; colouration; insertion; deletion; inversion; crow; tandem repeat; transposable element; gene expression;

    Sammanfattning : Heritable genetic variation is the raw material of evolution and can occur in many different forms, from altering single nucleotides to rearranging stretches of millions at once. DNA mutations that result in phenotypic differences are the basis upon which natural selection can act, leading to a shift of the frequency of those mutations. LÄS MER