Sökning: "transporter"

Visar resultat 1 - 5 av 429 avhandlingar innehållade ordet transporter.

  1. 1. EmrE, a puzzling transporter : Assembly, biogenesis and evolution of a dual-topology membrane protein

    Detta är en avhandling från Stockholm : Department of Biochemistry and Biophysics, Stockholm University

    Författare :Pilar Lloris-Garcerá; Stockholms universitet.; [2013]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; biokemi; Biochemistry;

    Sammanfattning : Biological membranes are the key to cell existence, as they are able to both isolate and connect their interior with the environment. Membranes are composed of lipids and proteins that create a semi-permeable barrier; because the lipid bilayer stops free diffusion of most molecules and ions, membrane proteins play an important role in connecting the interior of the cell with its environment. LÄS MER

  2. 2. Solute Carriers in Metabolism Regulation of known and putative solute carriers in the central nervous system

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Emilia Lekholm; Uppsala universitet.; Uppsala universitet.; [2017]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Solute Carriers; transporter; amino acid starvation; glucose metabolism; MFS; SV2; Medical Science; Medicinsk vetenskap;

    Sammanfattning : Solute carriers (SLCs) are membrane-bound transporter proteins, important for nutrient, ion, drug and metabolite transport across membranes. A quarter of the human genome codes for membrane-bound proteins, and SLCs make up the largest group of transporter proteins. LÄS MER

  3. 3. Structural studies of HDL and applications of EM on membrane proteins

    Detta är en avhandling från KTH Royal Institute of Technology

    Författare :Lin Zhu; KTH.; [2017]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; high density lipoprotein; rHDL; apoA-I; transmission electron microscopy; membrane protein; nanodisc; Salipro; transporter; Teknik och hälsa; Technology and Health;

    Sammanfattning : A large number of proteins interact with biological membranes, either integrated in the membrane (PepTSo2), embedded on a membrane surface (5-lipoxygenase) or encircling a cutout of lipid bilayer (apolipoprotein1 (apoA-I). They function as transporters, receptors or biocatalysts in cellular processes like inflammation or cholesterol transport which are touched upon here. LÄS MER

  4. 4. Atypical Solute Carriers Identification, evolutionary conservation, structure and histology of novel membrane-bound transporters

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Emelie Perland; Uppsala universitet.; [2017]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Major facilitator superfamily; solute carrier; transporter; protein expression; mRNA expression; phylogenetic clustering; orthologues; co-expression; subcellular location; nutrition.; Neuroscience; Neurovetenskap;

    Sammanfattning : Solute carriers (SLCs) constitute the largest family of membrane-bound transporter proteins in humans, and they convey transport of nutrients, ions, drugs and waste over cellular membranes via facilitative diffusion, co-transport or exchange. Several SLCs are associated with diseases and their location in membranes and specific substrate transport makes them excellent as drug targets. LÄS MER

  5. 5. Microarray analyses of the small intestinal mucosa during experimental and clinical cholera

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Carl-Fredrik Flach; Göteborgs universitet.; Gothenburg University.; [2005]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Vibrio cholerae; cholera toxin; microarray; transporter; intraepithelial lymphocytes; innate defence;

    Sammanfattning : Vibrio cholerae is a Gram-negative bacterium and the causative agent of cholera. The bacteria infect humans via contaminated water and food, and colonize the upper parts of the small intestine to cause disease. The disease is characterized by watery diarrhoea and most of its clinical features can be attributed to the secreted cholera toxin (CT). LÄS MER