Sökning: "transmembrane chaperone"

Visar resultat 1 - 5 av 14 avhandlingar innehållade orden transmembrane chaperone.

  1. 1. Interorganellar connectivity : From protein to lipid homeostasis

    Författare :Carlotta Peselj; Sabrina Büttner; Tim Levine; Stockholms universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Interorganellar connectivity; nucleus; NVJs; chronic lipid bilayer stress; glucose and phosphate exhaustion; nutritional regimes; transmembrane chaperone; IPTP; molekylär biovetenskap; Molecular Bioscience;

    Sammanfattning : Interorganellar connectivity is fundamental for the maintenance of organellar and cellular functionality and viability. This is achieved and maintained by a complex network of signaling cascades, vesicle trafficking between organelles as well as by establishment of direct physical contact at membrane contact sites (MCS). LÄS MER

  2. 2. Protein trafficking in the cell envelope of Escherichia coli : Identification and characterisation of a novel chaperone

    Författare :Hansjörg Götzke; Daniel Daley; Hans-Georg Koch; Stockholms universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Biochemistry; biokemi;

    Sammanfattning : The cell envelope of Gram-negative bacteria, like Escherichia coli, is composed of a cytoplasmic membrane, a periplasmic space containing a peptidoglycan layer and an outer membrane. About 30 % of all proteins are localised in the cell envelope. LÄS MER

  3. 3. The molecular chaperone CCT: Functions beyond folding

    Författare :Josefine Vallin; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Nyckelord :NATURVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; NATURAL SCIENCES; MEDICAL AND HEALTH SCIENCES; TRiC; Chaperonin; CCT oligomer; CCT monomer; cancer; p150Glued; gelsolin; STAT3;

    Sammanfattning : The chaperonin-containing tailless complex polypeptide 1 (CCT) is a eukaryotic ~1 MDa barrel shaped molecular chaperone, built up by eight distinct subunits and is required for the folding of the abundant cytoskeletal proteins actin and tubulin. CCT exists as an assembled oligomer, micro-complexes and as individual subunits in the cell. LÄS MER

  4. 4. Functional characterization of the yeast ER packaging chaperone Shr3p

    Författare :Fredrik Gilstring; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP;

    Sammanfattning : All living cells are enclosed by a plasma membrane (PM). The PM is a dynamic structure comprised of lipids and proteins that establishes and maintains the integrity of the cell. Cells utilize the PM to regulate metabolism by selectively altering the flow of metabolites entering the cell. The integral protein components of the PM, e. LÄS MER

  5. 5. Cotranslational protein biogenesis in Escherichia coli monitored by force profile analysis

    Författare :Felix Nicolaus; Gunnar von Heijne; Ross Dalbey; Stockholms universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Escherichia coli; cotranslational protein biogenesis; membrane protein; soluble protein; transmembrane helices; force profile analysis; arrest peptide; biokemi; Biochemistry;

    Sammanfattning : Proteins are a diverse class of biomolecules that carry out many essential functions across all organisms. They can either be found in aqueous compartments or embedded in biological membranes of the cell and are called soluble or membrane proteins, respectively. LÄS MER