Sökning: "transcriptomics"
Visar resultat 16 - 20 av 169 avhandlingar innehållade ordet transcriptomics.
16. Patterns in big data bioinformatics : Understanding complex diseases with interpretable machine learning
Sammanfattning : Alterations in the flow of genetic information may lead to complex diseases. Such changes are measured with various omics techniques that usually produce the so-called “big data”. Using interpretable machine learning (ML), we retrieved patterns from transcriptomics data sets. LÄS MER
17. Deradicalising Giardiasis Treatment
Sammanfattning : Giardia intestinalis is a unicellular parasite causing the disease giardiasis. This disease is mostly prevalent in low resource settings, mandating low-cost treatment options. LÄS MER
18. Molecular biology of barnacle Balanus improvisus settlement
Sammanfattning : The aim of this thesis was to investigate molecular mechanisms of various aspects of barnacle settlement, using the acorn barnacle Balanus improvisus. This barnacle is a common fouling species and a model organism for studies in settlement biology, in particular in relation to antifouling research. LÄS MER
19. Pan-cancer study of transcriptional responses to oncogenic somatic mutations
Sammanfattning : Cancer cells typically carry acquired somatic mutations in key cancer driver genes, which can be identified on the basis of recurrence in cancer cohorts. Such mutations may cause aberrant protein activity and altered gene expression in the nucleus, driving the cell toward a cancerous phenotype. LÄS MER
20. Data integration and visualization in type 2 diabetes research and care: From biological mechanisms to precision medicine
Sammanfattning : Background. Type 2 diabetes (T2D) is a complex heterogeneous disorder affecting multiple organs. Gene expression studies in organs central to T2D, such as pancreatic islets and skeletal muscle will help elucidate and disentangle molecular mechanisms underlying T2D. LÄS MER