Sökning: "transcriptional"

Visar resultat 11 - 15 av 1229 avhandlingar innehållade ordet transcriptional.

  1. 11. Rule-based Models of Transcriptional Regulation and Complex Diseases : Applications and Development

    Författare :Susanne Bornelöv; Jan Komorowski; Claes Wadelius; Joanna Polanska; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Histone modification; Transcription factor; Transcriptional regulation; Next-generation sequencing; Feature selection; Machine learning; Rule-based classification; Asthma; Allergy; Bioinformatik; Bioinformatics;

    Sammanfattning : As we gain increased understanding of genetic disorders and gene regulation more focus has turned towards complex interactions. Combinations of genes or gene and environmental factors have been suggested to explain the missing heritability behind complex diseases. LÄS MER

  3. 12. Molecular Metamorphosis in Transcriptional Regulation

    Författare :Malin Lüking; Johan Elf; Victor Muñoz; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Protein-DNA interactions; Facilitated diffusion; Binding Kinetics; Molecular Simulations; Fluorescence Microscopy; Biology with specialization in Structural Biology; Biologi med inriktning mot strukturbiologi; Biology with specialization in Molecular Biotechnology; Biologi med inriktning mot molekylär bioteknik;

    Sammanfattning : The foundation of all life is the interaction of molecules. Molecular interaction occurs in the tightly packed cytoplasm. In this crowded environment, the molecules need to be able to establish stable interactions with specific interaction partners, and with specific ones only. LÄS MER

  4. 13. Transcriptional patterns in inflammatory disease

    Författare :Johan Lindberg; Joakim Lundeberg; Eivind Hovig; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Gene expression profiling; transcription; microarray; rheumatoid arthritis; synovial tissue; variability; TNF‐α; anti‐TNF treatment; periodontitis; PGE2; Bioengineering; Bioteknik;

    Sammanfattning : In the studies this thesis is based upon, microarrays were applied to profilemRNA populations in biological samples to gain insights into transcriptionalpatterns and their relation to inflammatory disease.Rheumatoid arthritis (RA) is a chronic inflammatory disease, which leads todegradation of cartilage and bone. LÄS MER

  5. 14. Translational events and transcriptional coupling

    Författare :Flemming Jørgensen; Uppsala universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP;

    Sammanfattning : .... LÄS MER

  7. 15. Immunoglobulin genes in the rat : a structural and transcriptional analysis

    Författare :Marie-Louise Steén; Uppsala universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : .... LÄS MER