Sökning: "transcriptional profiling"

Visar resultat 6 - 10 av 94 avhandlingar innehållade orden transcriptional profiling.

  1. 6. Exploring the transcriptional space

    Författare :Joseph Bergenstråhle; Joakim Lundeberg; Jay W. Shin; KTH; []
    Nyckelord :Transcriptomics Spatial; Bioteknologi; Biotechnology;

    Sammanfattning : Transcriptomics promises biological insight into gene regulation, cell diversity, and mechanistic understanding of dysfunction. Driven by technological advancements in sequencing technologies, the field has witnessed an exponential growth in data output. Not only has the amount of raw data increased tremendously but it’s granularity as well. LÄS MER

  3. 7. Profiling the cancer proteome

    Författare :Sofia Waldemarson; Institutionen för immunteknologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cytologi; onkologi; cancer; Biotechnology; Bioteknik; cancerology; oncology; Cytology; iTRAQ; biomarkers; DIGE; two-dimensional gel electrophoresis; Proteomics;

    Sammanfattning : Cancer is a complex and heterogeneous disease where cells have started to grow uncontrolled and this disease remains a major health problem. Because of diffuse symptoms it often presents at a late stage. LÄS MER

  4. 8. Small Intestinal Neuroendocrine Tumor Analyses : Somatostatin Analog Effects and MicroRNA Profiling

    Författare :Su-Chen Li; Valeria Giandomenico; Kjell Öberg; Marco Volante; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Small intestinal neuroendocrine tumors; Somatostatin analogs; Laser-capture microdissection; Microarray profiling and microRNA profiling; Biology with specialization in Molecular Biology; Biologi med inriktning mot molekylärbiologi;

    Sammanfattning : Small intestinal neuroendocrine tumors (SI-NETs) originate from serotonin-producing enterochromaffin (EC) cells in the intestinal mucosa. Somatostatin analogs (SSAs) are mainly used to control hormonal secretion and tumor growth. However, the molecular mechanisms leading to the control of SI-NETs are unknown. LÄS MER

  5. 9. Human Dendritic Cells and the Regulation of Allergic Immune Responses

    Författare :Malin Lindstedt; Institutionen för immunteknologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; serology; transplantation; Immunologi; serologi; Immunology; allergic rhinitis; inflammation; transcriptional profiling; T cells; Dendritic cells; microarray;

    Sammanfattning : Dendritic cells (DC) are a heterogeneous lineage of bone-marrow-derived leukocytes that serve as the link between innate and adaptive immunity. They are professional antigen-presenting cells that play an important protective and regulatory role in both health and disease. LÄS MER

  7. 10. Dendritic cells in allergy In vitro models for studies of the human immune response

    Författare :Kristina Larsson; Institutionen för immunteknologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; transplantation; serology; Immunology; vaccine; Th2; transcriptional profiling; T cell; nanosphere; Immunologi; MUTZ-3; microarray; in vitro model; Allergic rhinitis; dendritic cell; serologi;

    Sammanfattning : This thesis, which is based on four original papers, deals with human dendritic cells (DCs) in immunity and allergy. DCs play a key role in the regulation of immune responses by acting as the sentinels of the immune system, specialized in the uptake of a diverse range of antigens. LÄS MER