Sökning: "transcriptional and translational regulation"

Visar resultat 11 - 15 av 78 avhandlingar innehållade orden transcriptional and translational regulation.

1. 11. Multiple regulatory inputs for hierarchical control of phenol catabolism by Pseudomonas putida

   Författare :W. K. Anjana Madhushani; Victoria Shingler; Livia Leoni; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; P. putida; Phenol catabolism; dmpR; dmp-System; 5’-LR; Carbon Catabolite Repression; Transcriptional Translational regulation; Crc; CrcZ; CrcY; Hfq;

   Sammanfattning : Metabolically versatile bacteria have evolved diverse strategies to adapt to different environmental niches and respond to fluctuating physico-chemical parameters. In order to survive in soil and water habitats, they employ specific and global regulatory circuits to integrate external and internal signals to counteract stress and optimise their energy status. LÄS MER

3. 12. Unraveling Mechanisms of Insulin Resistance in Type 2 Diabetes in Human Adipocytes : Role of extracellular signal regulated kinase 1/2 (ERK1/2) and forkhead box protein 01 (FOX01)

   Författare :Meenu Rohini Rajan; Peter Strålfors; Mats Söderström; Olga Göransson; Linköpings universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

   Sammanfattning : Type 2 Diabetes is characterized by hyperglycemia primarily caused due to insulin resistance in insulin responsive tissues and insufficient production of insulin by the β-cells. Insulin resistance appears to develop first in the expanding adipose tissue during caloric surplus and affects other tissues like liver and muscle by ectopic fat accumulation. LÄS MER

4. 13. Engineering Transcriptional Systems for Cyanobacterial Biotechnology

   Författare :Daniel Camsund; Peter Lindblad; Brian Pfleger; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Cyanobacteria; Synthetic biology; promoters; transcription; LacI; Gal4; Light-regulation; Chemistry with specialization in Microbial Chemistry; Kemi med inriktning mot mikrobiell kemi;

   Sammanfattning : Cyanobacteria are solar-powered cell factories that can be engineered to supply us with renewable fuels and chemicals. To do so robust and well-working biological parts and tools are necessary. LÄS MER

5. 14. Translational research of the quaking gene : Focusing on the conjunction between development and disease

   Författare :Bryn Farnsworth; Lina Emilsson; Roman Chrast; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; QKI; glia; oligodendrocyte; Alzheimer s; schizophrenia; zebrafish; statistics; morpholino; Biologi med inriktning mot evolutionär organismbiologi; Biology with specialization in Evolutionary Organismal Biology;

   Sammanfattning : Quaking (QKI) is an RNA binding protein involved in the post-transcriptional regulation of gene expression. Originally identified as the cause of hypomyelination in a mouse mutant, it has since been consistently implicated in a wide range of neurological diseases. LÄS MER

7. 15. Dissecting gene expression regulation in mouse embryonic stems

   Författare :Sandhya Malla; Francesca Aguilo; Filipe Pereira; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; molekylärbiologi; Molecular Biology;

   Sammanfattning : Every cell within an organism is derived from a single fertilized egg that undergoes cellular differentiation and development to generate mature specialized cells. Mouse embryonic stem cells (ESCs) derived from the inner cell mass (ICM) of the pre-implantation blastocyst have proven to be a model to study gene expression during differentiation and development. LÄS MER