Sökning: "transcription regulation"

Visar resultat 11 - 15 av 987 avhandlingar innehållade orden transcription regulation.

1. 11. Genetic and Genomic Analysis of Transcriptional Regulation in Human Cells

   Författare :Mehdi Motallebipour; Claes Wadelius; Gunnar Westin; Dirk Schübeler; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Transcription; ChIP-chip; ChIP-seq; genome-wide; transcription factors; microsatellite; epigenetic; Medical genetics; Medicinsk genetik;

   Sammanfattning : There are around 20.000 genes in the human genome all of which could potentially be expressed. However, it is obvious that not all of them can be active at the same time. Thus, there is a need for coordination achieved through the regulation of transcription. LÄS MER

3. 12. The interplay of transcription and chromatin regulation during embryonic development

   Författare :George Hunt; Mattias Mannervik; Eileen Furlong; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; transcription; chromatin; chromatin-modifiers; p300 CBP; Polycomb repression; promoter proximal Pol II pausing; molekylär biovetenskap; Molecular Bioscience;

   Sammanfattning : A fascinating aspect of multicellular development is the production of diverse cell types from an identical DNA genome, which depends on the ability to express different complements of genes across space and time. This thesis tries to address how the genome, within the chromatin structure that envelops it, is regulated to direct this complex process. LÄS MER

4. 13. Functional collaboration between HLH transcription factors in B cell development

   Författare :Ramiro Gisler; Stamcellscentrum (SCC); []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; E47; Early B cell Factor EBF ; Clinical genetics; Klinisk genetik; HLH proteins; transcription factors; gene expression; B cell development; transcription regulation;

   Sammanfattning : The cells in B cell development can be divided into several subgroups or fractions, e.g. early-pro-B-, pro-B, large-pre-B-, small-pre-B-, immature and mature B cells, where the stages reflect the maturity degree of the cells. LÄS MER

5. 14. Cyanobacterial Hydrogen Metabolism : Regulation and Maturation of Hydrogenases

   Författare :Ellenor Devine; Peter Lindblad; Karin Stensjö; Laurent Cournac; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; cyanobacteria; hydrogenase; hydrogenase specific protease; maturation; regulation; transcriptional studies; hupW; hoxW; hyp; NtcA; CalA; Biology; Biologi; Molecular biology; Molekylärbiologi; Microbiology; Mikrobiologi; Chemistry with specialization in Microbial Chemistry; Kemi med inriktning mot mikrobiell kemi;

   Sammanfattning : In times with elevated CO2 levels and global warming there is a need of finding alternatives to carbon based energy carriers. One such environmental friendly solution could be H2 produced by living organisms. LÄS MER

7. 15. Promoter Engineering for Cyanobacteria : An Essential Step

   Författare :Hsin-Ho Huang; Peter Lindblad; James Golden; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; synthetic biology; cyanobacteria; promoter; engineering; TetR; DNA breathing dynamics; transcription; regulation;

   Sammanfattning : Synthetic biology views a complex biological system as an ensemble in the hierarchy of parts, devices, systems, and networks. The practice of using engineering rules such as decoupling and standardization to understand, predict, and re-build novel biological functions from model-driven designed genetic circuits is emphasized. LÄS MER