Sökning: "transcription factor"

Visar resultat 11 - 15 av 1049 avhandlingar innehållade orden transcription factor.

1. 11. Functional collaboration between HLH transcription factors in B cell development

   Författare :Ramiro Gisler; Stamcellscentrum (SCC); []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; E47; Early B cell Factor EBF ; Clinical genetics; Klinisk genetik; HLH proteins; transcription factors; gene expression; B cell development; transcription regulation;

   Sammanfattning : The cells in B cell development can be divided into several subgroups or fractions, e.g. early-pro-B-, pro-B, large-pre-B-, small-pre-B-, immature and mature B cells, where the stages reflect the maturity degree of the cells. LÄS MER

3. 12. Determination of transcription factor binding specificities

   Författare :Arttu Jolma; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : The term "genetic code" refers to the way in which the information encoded in nucleic acids is converted into the amino-acid sequence of proteins. There is however also a second genetic code, one that is used by the cells to read the blueprints of the entire organism. LÄS MER

4. 13. Gene regulation by Early B-cell Factor (EBF)

   Författare :Peter Åkerblad; Immunologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; serology; Immunology; B-lymphocytes; Differentiation; Transcription; EBF; Gene regulation; transplantation; Immunologi; serologi;

   Sammanfattning : In this study we aimed at defining genes that are controlled by Early B-cell Factor (EBF), that could explain the severe block in B-cell development observed in EBF-/- mice. The fact that EBF appears to be important for the transcriptional control of genes encoding proteins in the pre-B and B-cell receptor complex implied to us that EBF could be a common regulator of other components in the pre-B and B-cell receptor. LÄS MER

5. 14. The Role of Hepatic Leukemia Factor in Hematopoiesis

   Författare :Karolina Komorowska; Avdelningen för molekylärmedicin och genterapi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hematopoiesis; Hematopoietic Stem Cells; knockout mice; HLF; Transcription Factor; aging;

   Sammanfattning : The development of therapeutic methods based on stem cells (e.g. cell therapy, activating regeneration and organ transplantation), known as regenerative medicine, is still a novel area in the field of life sciences. LÄS MER

7. 15. The acidic domain, the human version and the protein interaction of the ETS transcription factor SPI-C

   Författare :Robert Carlsson; Immunologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; serology; transplantation; Immunologi; serologi; Immunology; B-lymphocyte; phylogeny; STAT6; SPI-C; transcription;

   Sammanfattning : Primary infections and vaccination stimulates the immunesystem to produce memory cells that rapidly respond to reexposure of the same antigen. These memory responses are dependent on an adaptive type of immunity that sustains the reactivity of the immune system by long-lived memory immune cells. LÄS MER