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Visar resultat 1 - 5 av 16 avhandlingar som matchar ovanstående sökkriterier.

1. 1. To select one hand while using both : neural mechanisms supporting flexible hand dominance in bimanual object manipulation

   Författare :Anna Theorin; Roland Johansson; Fredrik Ullén; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; object manipulation; bimanual coordination; action selection; cerebral cortex; functional laterality; humans; hand; magnetic resonance imaging; transcranial magnetic stimulation; electromyography; Physiology; Fysiologi; fysiologi; Physiology;

   Sammanfattning : In daily activities, the brain regularly assigns different roles to the hands dependingon task and context. Yet, little is known about the underlying neural processes. Thiscertainly applies to how the brain, where each hemisphere primarily controls onehand, manages the between-hand coordination required in bimanual objectmanipulation. LÄS MER

3. 2. The effect of intermittent theta-burst stimulation over the dorsomedial prefrontal cortext on brain activity in depression

   Författare :Wiebke Struckmann; Robert Bodén; Jonas Persson; Malin Gingnell; Paul Hamilton; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; dorsomedial prefrontal cortex; iTBS; transcranial magnetic stimulation; Psychiatry; Psykiatri;

   Sammanfattning : Repetitive transcranial magnetic stimulation is an emerging alternative for treatment-resistant depression, with ongoing developments in stimulation protocols and treatment targets. As such, intermittent theta-burst stimulation (iTBS) delivered over the dorsomedial prefrontal cortex (dmPFC) has shown promise, however establishing a need for neuroimaging studies to further understand the treatment mechanisms. LÄS MER

4. 3. Negative symptoms, repetitive transcranial magnetic stimulation and heart rate variability in schizophrenia and depression

   Författare :Johan Bengtsson; Robert Bodén; Jonas Persson; Erik Olsson; Caroline Wass; Jimmi Nielsen; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; negative symptoms; psychotic disorders; affective disorders; non-invasive brain stimulation; transdiagnostics; psychometrics; autonomic nervous system; Psychiatry; Psykiatri;

   Sammanfattning : Negative symptoms comprise anhedonia, avolition, and blunted affect. Although first described in schizophrenia, these symptoms share phenomenology with the depressive state. Pharmacological treatment has not been successful in reducing negative symptoms. LÄS MER

5. 4. Brain Plasticity and Upper Limb Function After Stroke: Some Implications for Rehabilitation

   Författare :Påvel Lindberg; Jörgen Borg; Hans Forssberg; Margareta Engardt; Cornelius Weiller; Uppsala universitet; []
   Nyckelord :Neurosciences; Stroke; Upper Limb; Brain Plasticity; Functional MRI; Diffusion Tensor Imaging; Transcranial Magnetic Stimulation; Neurovetenskap;

   Sammanfattning : Neuroimaging and neurophysiology techniques were used to study some aspects of cortical sensory and motor system reorganisation in patients in the chronic phase after stroke. Using Diffusion Tensor Imaging, we found that the degree of white matter integrity of the corticofugal tracts (CFT) was positively related to grip strength. LÄS MER

7. 5. Amyotrophic lateral sclerosis (ALS) associated with superoxide dismutase 1 (SOD1) mutations in British Columbia, Canada : clinical, neurophysiological and neuropathological features

   Författare :Heather G. Stewart; Hiroshi Mitsumoto; Umeå universitet; []
   Nyckelord :ALS; SOD1; complete penetrance; incomplete penetrance; mis-diagnosis; upper motor neuron; clinical neurophysiology; transcranial magnetic stimulation; peristimulus time histogram; corticospinal pathway; cortical inhibition; cortical hyper-excitability;

   Sammanfattning : Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by loss of motor neurons and their supporting cells in the brain, brainstem and spinal cord, resulting in muscle paresis and paralysis including the bulbar (speech, chewing, swallowing) and respiratory muscles. The average age at onset is 55 years, and death due to respiratory failure occurs 2-5 years after symptom onset in ~ 85% of cases. LÄS MER