Sökning: "transaminase"

Visar resultat 11 - 15 av 23 avhandlingar innehållade ordet transaminase.

  1. 11. A biochemical and clinical study of GABA-transaminase and monoamine oxidase activities in the brain and blood platelets

    Författare :Fathi Mohamed Sherif; Uppsala universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : .... LÄS MER

  3. 12. Biocatalytic transamination with recombinant Saccharomyces cerevisiae: Challenges and opportunities

    Författare :Nora Weber; Teknisk mikrobiologi; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Saccharomyces cerevisiae; transamination; whole-cell biocatalysis; pyruvate; PLP; thiamine; reduction;

    Sammanfattning : Chiral building blocks are important molecules for synthesis of fine chemicals and pharmaceuticals. Biocatalysis has gained in relevance over traditional organic methods for synthesis of chiral compounds, as reactions can be performed at high enantio-selectivity and purity with environmentally friendly, simple, and cheap methods. LÄS MER

  4. 13. Chemo-enzymatic cascades for the synthesis of chiral high-value chemicals

    Författare :Lisa Marx; Per Berglund; Sabine Flitsch; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY;

    Sammanfattning : Chiral amines are frequent in today´s top selling pharmaceuticals. Classical organic synthesis of pharmaceuticals is often work intensive involving many synthesis steps, the use of protection group chemistry, heavy metal catalysts and chiral crystallization techniques. LÄS MER

  5. 14. Modeling environment effects on spectroscopic properties of biomarkers and catalytic mechanisms in enzymes

    Författare :Camilla Gustafsson; Patrick Norman; Daniel Escudero; KTH; []
    Nyckelord :Computational chemistry; spectroscopy; biocatalysis; water flow; biomarkers; Teoretisk kemi och biologi; Theoretical Chemistry and Biology;

    Sammanfattning : Arguably, humans are in need of both better diagnostic tools to prevent pro- gression of diseases as well as greener catalysts for synthesis of chemicals.Neurodegenerative diseases affecting neurons in the brain leads to demen- tias, where Alzheimer’s disease (AD) is the most prevalent. LÄS MER

  7. 15. Metabolic and pharmacokinetic study to enhance busulphan therapeutic efficacy

    Författare :Fadwa Benkessou; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Busulphan (Bu) is an alkylating agent used in high-doses as part of the conditioning regimen prior to hematopoietic stem cell transplantation (HSCT). HSCT is a curative treatment for hematological malignancies and other disorders. Bu can be administered by oral or intravenous route. LÄS MER