Sökning: "toxicity"

Visar resultat 21 - 25 av 965 avhandlingar innehållade ordet toxicity.

  1. 21. Cellular toxicity of quinones : Redox- and addition chemistry

    Författare :Karin Öllinger; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : Quinoid compounds are widely occurring in nature. They have cytotoxic properties and they are also used as antineoplastic agents. The cytotoxic properties can be explained by the ability of quinones to generate active oxygen species by redox cycling, by addition to cellular nucleophiles, and by inhibition of DNA transcription. LÄS MER

  3. 22. Clinical and tumour biology studies of Diffuse Large B-cell Lymphoma : with emphasis on comorbidity, toxicity and outcome

    Författare :Charlott Mörth; Gunilla Enblad; Kristina Drott; Uppsala universitet; []
    Nyckelord :DLBCL; autoimmune disease; cardiac toxicity; neurotoxicity; EFS; OS; Medicinsk vetenskap; Medical Science;

    Sammanfattning : Diffuse large B-cell lymphoma (DLBCL) is curable in around 70% when treated with standard immunochemotherapy R- CHOP (rituximab, cyclophosphamide, doxorubicin, vincristine and prednisone). Treatment related toxicity affecting survivors is a clinical problem as well as comorbidities influencing the possibility to give adequate treatment. LÄS MER

  4. 23. Melanosome transfer, photoreception and toxicity assays in melanophores

    Författare :Daniel Hedberg; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; colour change; melanophores; melanosome; intracellular transport; pigment transfer; photoreception; toxicity assay; Roundup; glyphosate;

    Sammanfattning : Many animals such as fish and frogs have developed the ability to change colour of their skin to adapt to the environment or to signal to other individuals. This ability is due to specialised skin cells called melanophores. LÄS MER

  5. 24. Therapy with 177Lu-octreotate - pharmacokinetics, dosimetry and kidney toxicity

    Författare :Maria Larsson; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; PRRT; 177Lu-octreotate; 111In-octreotide; dosimetry; biokinetics; scintigraphy; conjugate view method; renal function; renal toxicity; lysine; DMSA; 99mTc-DTPA; 99mTc-DMSA;

    Sammanfattning : 177Lu-octreotate is used for treatment of patients with somatostatin receptor expressing neuroendocrine tumors in some clinics using a standard schedule. Renal and bone marrow toxicity are the main limiting factors. LÄS MER

  7. 25. Survival and treatment related toxicity in classical Hodgkin lymphoma

    Författare :Ingemar Lagerlöf; Daniel Molin; Graham Collins; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hodgkin lymphoma; combined modality; late effects; treatment toxicity; radiotherapy; chemotherapy; long-term; follow-up; relative survival; years of life lost; excess mortality; excess morbidity; Oncology; Onkologi;

    Sammanfattning : Treating early-stage classical Hodgkin lymphoma (cHL) by adding radiotherapy to chemotherapy gives better disease control compared to chemotherapy only. With a low median age at diagnosis, the risk from cHL needs to be weighed against the risk of treatment toxicity. LÄS MER