Sökning: "toxicity"

Visar resultat 16 - 20 av 757 avhandlingar innehållade ordet toxicity.

  1. 16. Individually Tailored Toxicity-based Chemotherapy Studies on Patients with Primary and Metastatic Breast Cancer

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Henrik Lindman; Uppsala universitet.; [2003]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Oncology; breast cancer; tailored chemotherapy; toxicity-based dosing; high-dose therapy; MR imaging; G-CSF; epirubicin; docetaxel; cyclophosphamide; 5-fluorouracil; Onkologi; MEDICINE Surgery Oncology; MEDICIN Kirurgi Onkologi;

    Sammanfattning : Standard dosing of chemotherapy based on body surface area (BSA) results in large individual differences in toxicity due to a large inter-patient variability in pharmacokinetics (PK) and pharmacodynamics (PD). This results in under-dosing in certain patients with a potentially weaker antitumoral effect. LÄS MER

  2. 17. Advancing life cycle assessment of textile products to include textile chemicals. Inventory data and toxicity impact assessment

    Detta är en avhandling från ; Chalmers tekniska högskola; Gothenburg

    Författare :Sandra Roos; [2017]
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Chemicals; Textile; Toxicity; Life cycle assessment; LCA; Inventory; Impact assessment;

    Sammanfattning : Textile products are used by almost everybody throughout the world, fulfilling basic human needs such as keeping us warm and contributing to our social position. Every year the global textile industry delivers close to 100 million metric tonnes of new products to the market. LÄS MER

  3. 18. Cellular toxicity of quinones : Redox- and addition chemistry

    Detta är en avhandling från Linköping : Linköpings universitet

    Författare :Karin Öllinger; Linköpings universitet.; Linköpings universitet.; [1992]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICINE; MEDICIN;

    Sammanfattning : Quinoid compounds are widely occurring in nature. They have cytotoxic properties and they are also used as antineoplastic agents. The cytotoxic properties can be explained by the ability of quinones to generate active oxygen species by redox cycling, by addition to cellular nucleophiles, and by inhibition of DNA transcription. LÄS MER

  4. 19. Melanosome transfer, photoreception and toxicity assays in melanophores

    Detta är en avhandling från Linköping : Linköpings universitet

    Författare :Daniel Hedberg; Göteborgs universitet.; Gothenburg University.; [2009]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; colour change; melanophores; melanosome; intracellular transport; pigment transfer; photoreception; toxicity assay; Roundup; glyphosate;

    Sammanfattning : Many animals such as fish and frogs have developed the ability to change colour of their skin to adapt to the environment or to signal to other individuals. This ability is due to specialised skin cells called melanophores. LÄS MER

  5. 20. Therapy with 177Lu-octreotate - pharmacokinetics, dosimetry and kidney toxicity

    Detta är en avhandling från Göteborg : University of Gothenburg

    Författare :Maria Larsson; Göteborgs universitet.; Gothenburg University.; [2014]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; PRRT; 177Lu-octreotate; 111In-octreotide; dosimetry; biokinetics; scintigraphy; conjugate view method; renal function; renal toxicity; lysine; DMSA; 99mTc-DTPA; 99mTc-DMSA;

    Sammanfattning : 177Lu-octreotate is used for treatment of patients with somatostatin receptor expressing neuroendocrine tumors in some clinics using a standard schedule. Renal and bone marrow toxicity are the main limiting factors. LÄS MER