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Visar resultat 1 - 5 av 965 avhandlingar som matchar ovanstående sökkriterier.
1. Towards new computational tools for predicting toxicity
Sammanfattning : The toxicological screening of the numerous chemicals that we are exposed to requires significant cost and the use of animals. Accordingly, more efficient methods for the evaluation of toxicity are required to reduce cost and the number of animals used. LÄS MER
2. Environmental and health hazards of chemicals in plastic polymers and products
Sammanfattning : Plastics are extremely diverse in terms of chemical composition, properties and possible applications, and are widely distributed in the society and the environment. In the last 15 years the global annual production has doubled, reaching 245 million tons in 2008. LÄS MER
3. Anthracyclines : Toxicity and chemotherapy-induced mucositis
Sammanfattning : Anthracyclines belong to a class of cytostatic compounds that are commonly used to treat various types of cancers, including lymphoma, breast cancer and primary liver cancer. The aim of this thesis was to study how two anthracyclines, doxorubicin and idarubicin, induced cytotoxicity in tumor cells, as well as their off-target effect on the gastrointestinal system. LÄS MER
4. Comparative avian developmental toxicity of PFAAs
Sammanfattning : Perfluoroalkyl acids (PFAAs) are persistent organic pollutants that can commonly be found in environmental matrixes and wildlife from all over the globe. The PFAAs have been used in applications such as water and dirt repelling treatments for textiles, oil-resistant paper coatings and fire-fighting foams. LÄS MER
5. Analysis of Perfluoroalkyl Acids in Swedish Biota : Temporal trends, tissue distribution and toxicity
Sammanfattning : Perfluorinated alkyl acids (PFAS) are ubiquitous environmental contaminants. They are found in high concentrations in top predators worldwide, with perfluorooctane sulfonate (PFOS) as the predominant compound. LÄS MER