Sökning: "torbjörn gräslund"
Visar resultat 1 - 5 av 14 avhandlingar innehållade orden torbjörn gräslund.
1. Protein Engineering by Directed Evolution and Rational Design
Sammanfattning : .... LÄS MER
2. Targeting HER2-expressing tumors with potent drug conjugates and fusion toxins based on scaffold proteins
Sammanfattning : Targeted therapy is an emerging treatment for a variety of cancers. Small- sized scaffold proteins are an alternative to conventional antibody-based targeting molecules. LÄS MER
3. Tools in biocatalysis : enzyme immobilisation on silica and synthesis of enantiopure amines
Sammanfattning : This thesis presents two techniques in the field of biocatalysis: An enzyme immobilisation method based on the His6-tag for attachment on modified silica oxide beads, and it’s employment in aqueous and organic medium for synthesis applications. The method functions as a one step extraction and immobilisation protocol. LÄS MER
4. Biochemical and structural characterization of two thermostable carbohydrate-active enzymes with potential in biotechnological applications
Sammanfattning : .... LÄS MER
5. Engineering of Affibody molecules for Radionuclide Molecular Imaging and Intracellular Targeting
Sammanfattning : Affibody molecules are small (7 kDa) affinity proteins of non-immunoglobulin origin that have been generated to specifically interact with a large number of clinically important molecular targets.In this thesis, Affibody molecules have been employed as tracers for radionuclide molecular imaging of HER2- and IGF-1R-expressing tumors, paper I-IV, and for surface knock-down of EGFR, paper V. LÄS MER