Sökning: "tissue necrosis"

Visar resultat 1 - 5 av 158 avhandlingar innehållade orden tissue necrosis.

1. 1. Tissue kallikrein: pathophysiological role in acute pancreatitis

   Författare :Mats Bläckberg; Helsingborg Kliniska Vetenskaper; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; acute pancreatitis; aprotinin; alpha-macroglobulin; alpha1-proteinase inhibitor; turn over; kinin B2 receptor; kallidin; bradykinin; Tissue kallikrein; kallistatin; Surgery; orthopaedics; traumatology; Kirurgi; ortopedi; traumatologi;

   Sammanfattning : Tissue kallikrein releases pharmacollogically highly active kinins from kininogen. Many other enzymes may also release kinins. The aim of the study was to clarify the pathophysiological role of tissue kallikrein in acute pancreatitis. Two sensitive and specific radioimmunoassays for porcine and human tissue kallikrein were developed. LÄS MER

3. 2. Cell therapy for denervated tissue

   Författare :Roine El-Habta; Ludvig J. Backman; Paul J. Kingham; Patrik Danielson; António Salgado; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; adipose tissue-derived stem cell; cell therapy; denervation; differentiation; myoblast; peripheral nerve injury; proliferation; regeneration; skeletal muscle; stromal vascular fraction; survival; tendon; cellforskning; cell research; Medical Cell Biology; medicinsk cellbiologi;

   Sammanfattning : Background: Peripheral nerve injury results in denervation of tendons and muscles. The biology of denervated muscle has been well studied but little is known about the associated tendons. LÄS MER

4. 3. Prognostic factors in soft tissue sarcoma. Tissue microarray for immunostaining, the importance of whole-tumor sections and time-dependence

   Författare :Jacob Engellau; Bröstcancer-genetik; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; growth pattern; time-dependence; P-glycoprotein Pgp ; CD44; β-catenin; cyclin A; bcl-2; p53; Ki-67; immunohistochemistry IHC ; whole-tumor sections; tissue microarray TMA ; Soft tissue sarcoma; prognostic factors; Cytology; oncology; cancerology; Cytologi; onkologi; cancer;

   Sammanfattning : In adult soft tissue sarcoma (STS) of the extremities and trunk wall, improved prognostic factors are needed to identify patients at high-risk for metastasis. Various factors are included in the many prognostic systems currently in use and the prognostic value of immunohistochemical (IHC) expression of biological markers is unclear. LÄS MER

5. 4. Regional fluxes of tissue plasminogen activator in porcine endotoxemia

   Författare :Annette Nyberg; Göteborgs universitet; []
   Nyckelord :pig; endotoxin; tissue type plasminogen activator; plasminogen activator inhibitor; tumor necrosis factor ?;

   Sammanfattning : Formation of fibrin clots in the microcirculation during severe sepsis contributes to organ failure, frequently involving the lungs and the splanchnic organs. Tissue type plasminogen activator, tPA, is the key activator of intravascular fibrinolysis with plasminogen activator inhibitor type-1, PAI-1, as its main inhibitor. LÄS MER

7. 5. Imaging of soft tissue tumors

   Författare :Hildur Einarsdóttir; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : The aim of this project on soft tissue tumors, was to evaluate existing imaging methods and test new Magnetic Resonance Imaging (MRI) sequences for diagnosis and assessment of cytotoxic therapy and to relate the imaging studies to cytology to explore the limitations of each procedure. Patients and method: The studies were based on patients with a soft tissue lesion diagnosed and treated at the Orthopedic Tumor Service at the Karolinska Hospital 1990-2003. LÄS MER