Sökning: "tissue ischemia"
Visar resultat 1 - 5 av 147 avhandlingar innehållade orden tissue ischemia.
1. Exploring Intestinal Ischemia : An experimental study
Sammanfattning : Background and aims: Unrecognized intestinal mucosal ischemia in severely ill patients may trigger development of multiple organ failure. Such ischemia can be evaluated by intraluminal tonometry reflecting mucosal PCO2 and intramucosal pH (pHi). LÄS MER
2. Brain Tissue Oxygenation in Traumatic Brain Injury : Experimental and Clinical Studies
Sammanfattning : Traumatic brain injury (TBI) is a major cause of death and disability. TBI is frequently followed by cerebral ischemia which is a great contributor to secondary brain damage. The main causes of cerebral ischemia are pathophysiological changes in cerebral blood flow and metabolism. LÄS MER
3. Intestinal ischemia and reperfusion. Proinflammatory response and organ dysfunction
Sammanfattning : Intestinal I/R is considered to be an important initiating event in several pathophysiological conditions such as trauma, bleeding, sepsis and pancreatitis, frequently leading to concomitant both single and potentially multiple organ dysfunction. The purpose of this thesis was to study mechanims underlying the development of multiple organ dysfunction, with special focus on intercellular proinflammatory regulation in the concurrent development of tissue injury. LÄS MER
4. Electropermeabilization in Experimental Tumour Treatment: Dosimetry and Tissue Effects
Sammanfattning : Short, electric high-voltage pulses can be used to transiently increase the permeability of cell membranes without significant loss of cell viability. During this period of time, extracellular and normally non-permeant, molecules are accessed the cytoplasm and the cell nucleus. LÄS MER
5. Improved bioenergetic recovery during experimental ischemia and reperfusion by irradiation
Sammanfattning : Prolonged ischemia and reperfusion frequently occur during clinical operations. The bioenergetic status decreases during ischemia and reactive oxygen species (ROS) are formed during reperfusion, which may lead to irreversible tissue injury. LÄS MER