Sökning: "tissue expression"
Visar resultat 16 - 20 av 1928 avhandlingar innehållade orden tissue expression.
16. Tumor instructed normal tissue : studies of potential extratumoral biomarkers and therapeutic targets in prostate cancer
Sammanfattning : Prostate cancer is the most common cancer in men in Sweden and but luckily the majority of the patients will carry on their life without any consequences from the disease. Unfortunately, some will develop aggressive tumors and eventually die. LÄS MER
17. Microarray analysis of gene expression in human adipocytes and adipose tissue
Sammanfattning : Obesity has reached epidemic proportions worldwide and is associated with several serious conditions such as insulin resistance, type 2 diabetes, hyperlipidemia and atherosclerosis. Adipose tissue exerts important endocrine and immune functions through the release of adipokines. LÄS MER
18. Antibody-based Profiling of Expression Patterns using Cell and Tissue Microarrays
Sammanfattning : In this thesis, methods to study gene and protein expression in cells and tissues were developed and utilized in combination with protein-specific antibodies, with the overall objective to attain greater understanding of protein function.To analyze protein expression in in vitro cultured cell lines, a cell microarray (CMA) was developed, facilitating antibody-based protein profiling of cell lines using immunohistochemistry (IHC). LÄS MER
19. Regulation of tissue factor expression in myeloid and monocytic leukaemia cells
Sammanfattning : Tissue factor (TF) is a transmembrane glycoprotein that initiates the blood coagulation cascade and is also involved in cell migration, tumour metastasis and angiogenesis. Pathologic expression of tissue factor by monocytes contributes to several thrombotic complications like acute coronary artery disease and disseminated intravascular coagulation. LÄS MER
20. Bioimaging for analysis of protein expression in cells and tissues using affinity reagents
Sammanfattning : The detection and analysis of biomolecules, such as proteins, are of great interest since these molecules are fundamental for life and our health. Due to the complexity of biological processes, there is a great advantage of studying proteins in their natural context, for example by using bioimaging. LÄS MER