Sökning: "timolol"

Hittade 4 avhandlingar innehållade ordet timolol.

  1. 1. Pooling Data from Similar Randomized Clinical Trials Comparing Latanoprost with Timolol; Medical Results and Statistical Aspects

    Författare :Katarina Hedman; Albert Alm; Adam Taube; T Joseph Sheehan; Uppsala universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Ophtalmology; mean intraocular pressure; target intraocular pressure; latanoprost; timolol; open-angle glaucoma; ocular hypertension; trial design; Oftalmiatrik; Ophtalmology; Oftalmologi; Ophtalmology; oftalmiatrik;

    Sammanfattning : Two different principles were studied. 1st - statistical analysis techniques were used to obtain medical results from a patient population. 2nd - the patient population was used to study the statistical analysis techniques. LÄS MER

  3. 2. Aspects of aqueous humor dynamics : Studies in vivo and in vitro

    Författare :Maria Samuelsson-Almén; Uppsala universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Physiology and anatomy; Aqneous humor flow; intraocular pressure; adenylate cyclase; nonpigmented ciliary epithelium; pituitary adenylate cyclase-activating polypeptide; vasoactive intestinal polypeptide; dopamine; prostaglandin; Fysiologi och anatomi; Physiology and pharmacology; Fysiologi och farmakologi; Physiology; fysiologi;

    Sammanfattning : The purpose of the present investigation was to study the effects of PGF2α-l-isopropylester, some neuropeptides, and pharmacological agents on aqueous humor dynamics and intraocular pressure (IOP) in vivo and on adenylate cyclase activity in the nonpigmented ciliary epithelium (NPE) in vitro.Pituitary adenylate cyclase-activating polypeptide (PACAP) and vasoactive intestinal polypeptide (VIP) caused a dose-dependent increase in cAMP formation, indicating that the NPE contains receptors for PACAP and VIP coupled to adenylate cyclase activation. LÄS MER

  4. 3. Chiral Separation of Amines by Non-Aqueous Capillary Electrophoresis using Low Molecular Weight Selectors

    Författare :Ylva Hedeland; Curt Pettersson; Ulf Bondesson; Lars Blomberg; Uppsala universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Pharmaceutical chemistry; Chiral Separation; Non-Aqueous Capillary Electrophoresis; Enantioresolution; Electro-osmotic Flow; Pharmaceuticals; Enantiomeric Amines; Low Molecular Weight Selector; Farmaceutisk kemi; Kemi med inriktning mot analytisk kemi; Chemistry with specialization in Analytical Chemistry; Analytical Pharmaceutical Chemistry; Analytisk farmaceutisk kemi;

    Sammanfattning : Three chiral selectors (diketogulonic acid, benzoxycarbonylglycylproline and ketopinic acid) have been introduced for enantioseparation of pharmacologically active amines in non-aqueous capillary electrophoresis. The use of organic solvents, instead of aqueous buffers in the background electrolyte facilitated ion-pair formation between the analytes and the chiral selectors. LÄS MER

  5. 4. Preparation and characterisation of biodegradable microspheres for the delivery of bioactive compounds

    Författare :Cecilia Sturesson; Uppsala universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacy; FARMACI; PHARMACY; FARMACI; galenisk farmaci; Pharmaceutics;

    Sammanfattning : The incorporation of bioactive compounds into biodegradable polymer microspheres has several advantages. Firstly, the drug substance is protected from physiological degradation. Secondly, using microspheres from polymers with different degradation mechanisms, it is possible to design different release profiles with desired release rates. LÄS MER