Sökning: "ticagrelor"

Visar resultat 1 - 5 av 19 avhandlingar innehållade ordet ticagrelor.

1. 1. Improving outcomes in patients with coronary heart disease using national registers and platelet function testing

   Författare :Sasha Koul; Kardiologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; STEMI; NSTEMI; ACS; Ticagrelor; clopidogrel; prasugrel; treatment delays; bivalirudin; heparin; platelet function testing;

   Sammanfattning : Introduction: Ischemic heart disease is the leading cause of death worldwide. The aims of this thesis were to evaluate different contemporary approaches in coronary care with regard to mortality and myocardial infarction. LÄS MER

3. 2. Platelet activation and aggregation: Clinical and experimental studies

   Författare :Sukhi Singh; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Platelet concentrate; Adrenaline; Noradrenaline; Ticagrelor; Platelet aggregation; Platelet activation;

   Sammanfattning : Background: Dual antiplatelet therapy with acetylsalicylic acid (ASA) and the adenosine diphosphate (ADP)-receptor antagonist ticagrelor increases the risk of bleeding complications during cardiac surgery. The overall aim of this thesis was to identify and evaluate current and potential methods to reduce and prevent bleeding complications in patients with ongoing antiplatelet therapy. LÄS MER

4. 3. Platelet Inhibition, Revascularization, and Risk Prediction in Non-ST-elevation Acute Coronary Syndromes

   Författare :Daniel Lindholm; Stefan James; Christoph Varenhorst; James de Lemos; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; coronary artery disease; myocardial infarction; acute coronary syndrome; non-ST-elevation acute coronary syndrome; P2Y12 inhibitors; ticagrelor; biomarkers; revascularization; percutaneous coronary intervention; risk prediction; Cardiology; Kardiologi;

   Sammanfattning : Cardiovascular disease is the leading cause of death worldwide and ischemic heart disease is the most common manifestation. Despite improved outcomes during the last decades, patients with acute coronary syndromes (ACS) are still at substantial risk of recurrent ischemic events and mortality. LÄS MER

5. 4. Kinetic Models in Life Science — Contributions to Methods and Applications

   Författare :Joachim Almquist; Stiftelsen Fraunhofer-Chalmers Centrum för Industrimatematik (FCC); []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NLME modeling; kinetic models; FOCE; Mig1; cell-to-cell variability; pharmacokinetics; parameter estimation; ticagrelor; atrial fibrillation; Kv1.5;

   Sammanfattning : Kinetic models in life science combine mathematics and biology to answer questions from areas such as cell biology, physiology, biotechnology, and drug development. The idea of kinetic models is to represent a biological system by a number of biochemical reactions together with mathematical expressions for the reaction kinetics, i.e. LÄS MER

7. 5. Cardiovascular events after acute coronary syndrome with special reference to ischemic stroke

   Författare :Anders Ulvenstam; Thomas Mooe; Bo Carlberg; Per Tornvall; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cardiovascular disease; acute coronary syndrome; acute myocardial infarction; ischemic stroke; time trends; risk factors; P2Y12-receptor inhibitor; ticagrelor; major adverse cardiovascular events; revascularization; lipid-lowering therapy; Medicine; medicin; kardiologi; Cardiology;

   Sammanfattning : Background: Acute coronary syndrome (ACS) encompasses acute myocardial infarction (AMI) and unstable angina (UA). It is a global major cause of morbidity and mortality in both the short and long terms. LÄS MER