Sökning: "tibolone"

Hittade 4 avhandlingar innehållade ordet tibolone.

  1. 1. Mammographic breast density and postmenopausal hormone therapy

    Författare :Eva Lundström; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Mammographic breast density; mammography; menopause; hormone therapy; tibolone; low dose intrauterine progestogen; Syndecan-1.;

    Sammanfattning : Breast cancer is the most frequent malignancy among women in the western world. More than one million women are estimated to be diagnosed with the disease every year. The breast is a target organ for sex steroids and hormonal treatments have been found to increase the risk for breast cancer. LÄS MER

  2. 2. Hormone therapy and the breast : aspects on proliferation, apoptosis and mammographic density

    Författare :Peter Conner; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Breast cell proliferation; fine needle aspiration cytology; menopause; hormone replacement therapy; tibolone; mammographic breast density; continuous combined hormone therapy; p53; apoptosis; cynomolgus macaques.;

    Sammanfattning : Breast cancer is the major malignancy among women in the western world. The breast is clearly a target organ for sex steroid hormones and hormonal treatments have been associated with an increased risk of breast cancer. Still, basic knowledge as to how sex steroids influence the normal breast is remarkably poor. LÄS MER

  3. 3. Testosterone and the postmenopausal breast : aspects on cell proliferation and mammographic density

    Författare :Marie Hofling; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Menopause; testosterone; breast cell proliferation; fine needle aspiration biopsy; mammographic density; Syndecan-1; androgen receptor; cynomolgus macaques;

    Sammanfattning : The breast is a target organ for sex steroids, and hormonal treatments have been associated with a risk of breast cancer. There is increasing interest in androgen treatment for postmenopausal women. Testosterone has been shown to improve bone density, body composition, mood, psychosexual function and general well-being. LÄS MER

  4. 4. Hormonal regulation of the primate uterus : effects of hormone treatment and lifestyle intervention

    Författare :Mariana Hulchiy; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :endometrium;

    Sammanfattning : The uterus is a major hormone-responsive reproductive organ in primates. Hormones promote their effect via different pathways. Receptors involved in steroid hormone, thyroid hormone and insulin signaling have been found in the endometrium. LÄS MER