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  1. 1. Autoimmune thyroiditis : a clinical, epidemiological and immunological study with special reference to transient aggravation in the postpartum period

    Författare :Rolf Jansson; Uppsala universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : .... LÄS MER

  2. 2. Aspects of beta cell and thyroid autoimmunity in children

    Författare :Bengt Lindberg; Pediatrisk endokrinologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pediatrics; virus; vaccination; type 1 diabetes mellitus; thyroiditis; allergy; autoantibodies; Pediatri;

    Sammanfattning : The two most common autoimmune endocrine diseases in children are autoimmune thyroiditis (AIT) and Type 1 (insulin-dependent) diabetes mellitus (IDDM). Autoantibodies (ab) can be found several years before clinical diagnosis in both diseases. LÄS MER

  3. 3. Studies on the etiology of endemic goiter in the Sudan : The role of pearl millet

    Författare :Abdelsalam Elnour; Uppsala universitet; []
    Nyckelord :Medical sciences; Pearl millet; endemic goiter; thyroid hormones; thyroiditis; traditional fermentation; heattreatment; flavonoid; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Nutrition; näringslära;

    Sammanfattning : Endemic thyroid disorders (ETD) are major health problems worldwide. Although the major role of iodine deficiency in the etiology of ETD is well founded, other factors have been shown to contribute to its etiology as well. LÄS MER

  4. 4. Autoimmunity in glomerulonephritis; serological diagnosis and clinical outcome with special reference to Wegener´s granulomatosis and microscopic polyangiitis

    Författare :Kerstin Westman; Njurmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Wegener´s granulomatosis; vasculitis; thyroid peroxidase antibodies; proteinase 3; myeloperoxidase; antineutrophil cytoplasmic antibodies; ANCA; thyroiditis; autoantibodies; glomerulonephritis; microscopic polyangiitis; Urology; nephrology; Urologi; nefrologi;

    Sammanfattning : Autoantibodies of different specificites have been described in association with glomerulonephritis and therefore the aim of this thesis was to improve our knowledge of the different manifestations of autoimmune phenomena which are involved in the glomerulonephritides. Special reference is made to Wegener´s granulomatosis (WG) and microscopic polyangiitis (MP) which are frequently associated with the prevalence of anti-neutrophil cytoplasmic antibodies (ANCA). LÄS MER

  5. 5. Aspects of chronic autoimmune thyroiditis in children and adolescents

    Författare :Johan Svensson; Pediatrisk endokrinologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; adolescents; thyroid autoantibodies; enterovirus infection; thyroid ultrasonography; reference standard; goiter; chronic autoimmune thyroiditis; levothyroxine treatment; Medicin människa och djur ; Medicine human and vertebrates ; children;

    Sammanfattning : The aims of this thesis were to 1) compare different methods for detection of antibodies against thyroglobulin (TgAb) and thyroid peroxidase (TPOAb), particulary in children with chronic autoimmune thyroditis (AIT), 2) investigate if maternal enterovirus infection is a risk factor for development of AIT in offspring, 3) ascertain the prevalence of thyroid autoantibodies in cord blood sera from children who later developed AIT, 4) develop a new reference standard for interpretation of normative thyroid volumes in Swedish children, and 5) evaluate the effect of Levothyroxine (L-thyroxine) treatment on thyroid size in children and adolescents with AIT. We found that 1) Methods based on radioimmunoassay (RIA) were more efficient in detecting both TgAb and TPOAb in children with AIT than methods based on agglutination. LÄS MER