Sökning: "thyroid hormone receptor"

Visar resultat 1 - 5 av 54 avhandlingar innehållade orden thyroid hormone receptor.

  1. 1. Life without thyroid hormone receptors

    Detta är en avhandling från Stockholm : Karolinska Institutet, Department of Cell and Molecular Biology

    Författare :Sten Göthe; Karolinska Institutet.; Karolinska Institutet.; [2003]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Thyroid hormone (TH) has many important functions during development and in the adult individual. It reaches its target cells via the blood system and binds its receptor (TR) located within the cell nucleus where the receptor regulates target genes. This hormone-mediated gene regulation is a finely tuned interplay of numerous parameters. LÄS MER

  2. 2. Thyroid hormone receptor expression in cardiovascular disease and pharmacology

    Detta är en avhandling från Stockholm : Karolinska Institutet, Department of Medicine at Huddinge University Hospital

    Författare :Shiva Shahrara; Karolinska Institutet.; Karolinska Institutet.; [1999]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TR mRNA; amiodarone; propranolol; heart rate; Quantitative RT-PCR; Western blot; Northern blot; mRNA and protein distribution; chronic valvular disease; Mated cardiomyopathy; AT- I cardiomyocytes; mouse myocardium;

    Sammanfattning : The heart is a major target organ for thyroid hormone actions. Thyroid hormone exerts effects on the myocardium, which are mediated by specific nuclear receptors. The thyroid hormone receptors (TR) are members of the steroid hormone receptor superfamily. LÄS MER

  3. 3. Thyroid hormone receptors in liver metabolism

    Detta är en avhandling från Stockholm : Karolinska Institutet, Department of Cell and Molecular Biology

    Författare :Hjalmar Gullberg; Karolinska Institutet.; Karolinska Institutet.; [2002]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Thyroid hormone has a profound impact on mammalian metabolism; hypothyroidism causes decreased metabolic rate and increased serum cholesterol levels. One major target organ for the hormone is the liver, the most important metabolic organ in mammals, that balances anabolism of carbohydrates and lipids against catabolism. LÄS MER

  4. 4. Recurrent unexplained first-trimester miscarriage. Effects of acetylcalicylic acid, platelet aggregation and thyroid disease

    Detta är en avhandling från Göteborgs universitet

    Författare :Lennart Blomqvist; Göteborgs universitet.; Gothenburg University.; [2019]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Acetylsalicylic acid; recurrent miscarriage; platelet aggregation; pregnancy; early pregnancy; first-trimester; live birth; impedance aggregometry; thyroid stimulating hormone; levothyroxine; thyroid peroxidase antibody; arachidonic acid-induced platelet aggregation; platelet activators;

    Sammanfattning : Recurrent unexplained first-trimester miscarriage. Effects of acetylsalicylic acid, platelet aggregation and thyroid disease. Lennart Blomqvist, Department of Obstetrics and Gynecology, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Sweden, 2019. LÄS MER

  5. 5. Expression and Function of Thyroid Hormone Receptor Alpha 1 in the Brain

    Detta är en avhandling från Stockholm : Karolinska Institutet, Dept of Cell and Molecular Biology

    Författare :Karin Wallis; Karolinska Institutet.; Karolinska Institutet.; [2011]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Thyroid hormone is fundamentally important for development and maintenance of adult brain functions and maternal hypothyroxinemia during pregnancy can lead to a severe mental retardation known as endemic cretinism. The first realization that endemic cretinism is caused by iodine deficiency and its association with thyroid hormone was made a century ago; this eventually resulted in dietary supplementation programmes, e. LÄS MER