Sökning: "thymidine"

Visar resultat 11 - 15 av 93 avhandlingar innehållade ordet thymidine.

  1. 11. Prostasomes as Diagnostic, Prognostic and Therapeutic Vesicles

    Författare :Louise Dubois; Anders Larsson; Lucia Mincheva-Nilsson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Exosomes; Prostasomes; Lipid rafts; Bioengineered vesicles; Prostate cancer; Purinergic receptors; Thymidine kinase 1; Medical Biochemistry; Medicinsk biokemi;

    Sammanfattning : This thesis explores prostasomes and their ability to be used as a new diagnostic tool for prostate cancer. Alongside diagnosis, this thesis also suggests prostasomes as a tool for prognosis and therapeutic treatment in patients with prostate cancer. LÄS MER

  3. 12. Antibiotics and infusion phlebitis. Clinical and experimental studies

    Författare :Peter Lanbeck; Enheten för infektionssjukdomar; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Infections; HUVEC; endothelium vascular; Infektioner; ICAM-1; 3H-thymidine incorporation; cloxacillin; dicloxacillin; phlebitis epidemiology; Antibiotics; phlebitis chemically induced;

    Sammanfattning : Intravenous administration of antibiotics is often followed by infusion phlebitis. In this condition are vessel irritation, inflammation and sometimes superficial thrombosis included. In this thesis, the risk for infusion phlebitis for various antibiotics has been evaluated in a clinical study in 550 patients. LÄS MER

  4. 13. Molecular properties of serum thymidine kinase 1 and use of the canine enzyme in disease monitoring

    Författare :Hanan Sharif; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
    Nyckelord :LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES;

    Sammanfattning : Thymidine kinase 1 (ATP: thymidine 5'-phosphotransferase, EC 2.7.1.21, TK1) catalyzes the transfer of the gamma phosphate group from a phosphate donor to the 5´- hydroxyl group of thymidine to form thymidine monophosphate, which is converted to thymidine triphosphate and then utilized in DNA synthesis. LÄS MER

  5. 14. Neural stem cell-mediated enhanced gene therapy of malignant gliomas using a novel plant thymidine kinase

    Författare :Zahidul Khan; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Malignant glioma; suicide gene therapy; bystander effect; gap junction; neural stem cell; 4-phenylbutyrate; epigenetics; cell differentiation;

    Sammanfattning : Malignant gliomas are the most common brain tumors in adults. Approximately, 190,000 new patients are diagnosed with malignant gliomas worldwide every year. Unfortunately, the prognosis of malignant gliomas still remains very poor, despite advances in management. LÄS MER

  7. 15. Diagnostic implications of the molecular forms and levels of serum thymidine kinase 1 in different canine malignancies

    Författare :Kiran Kumar Jagarlamudi; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
    Nyckelord :LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES;

    Sammanfattning : Thymidine kinase 1 (ATP: thymidine 5’- phosphotransferase, EC 2.1.7. 21, TK1) is a cellular enzyme involved in salvage pathway for DNA precursor synthesis. LÄS MER