Sökning: "thymidine phosphorylase"
Hittade 3 avhandlingar innehållade orden thymidine phosphorylase.
1. Experimental and population-based studies on colorectal cancer - Thymidine phosphorylase as a potential biomarker
Sammanfattning : Background: Colorectal cancer (CRC) is one of the most common malignancies, and the only reliable treatment option for cure is surgery. Method: Quantitative real-time polymerase chain reaction was used to analyze the gene expression of the enzyme thymidine phosphorylase (TP), which was related to prognostic factors (paper I, n=254), evaluated as a predictive factor (paper III, n=125), and assessed by change of treatment (paper II, n=28). LÄS MER
2. Targeting the nucleotide metabolism of the mammalian pathogen Trypanosoma brucei
Sammanfattning : Trypanosoma brucei causes African sleeping sickness in humans and Nagana in cattle. There are no vaccines available against the disease and the current treatment is also not satisfactory because of inefficacy and numerous side effects of the used drugs.T. LÄS MER
3. Targets and strategies for drug development against human African sleeping sickness
Sammanfattning : Trypanosoma brucei is a causative agent of African sleeping sickness. It is an extracellular parasite which circulates in the blood, lymph and eventually invades the central nervous system. LÄS MER