Sökning: "threading intercalation"

Visar resultat 1 - 5 av 11 avhandlingar innehållade orden threading intercalation.

  1. 1. DNA Interaction Dynamics of Ruthenium(II) Complexes

    Författare :Fredrik Westerlund; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; fluorescence; ruthenium; polarized spectroscopy; threading; sequence selectivity; photophysics; binding kinetics; DNA; intercalation;

    Sammanfattning : DNA-binding of small synthetic ligands is of great importance in a number of different applications, from medicine to molecular biology. This thesis focuses on interactions between DNA and ruthenium(II) complexes, in particular the dimers [µ-bidppz(L)4Ru2]4+ (L=1,10-phenanthroline (P) or L=2,2-bipyridine (B)). LÄS MER

  3. 2. On semirigid binuclear ruthenium complexes and DNA : binding modes and kinetics

    Författare :Fredrik Westerlund; Chalmers tekniska högskola; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; binding kinetics; polarized light spectroscopy; threading; intercalation; SDS-sequestered dissociation; FRET; DNA; ruthenium complexes;

    Sammanfattning : .... LÄS MER

  4. 3. Recognition and Visualization of Nucleic Acids

    Författare :Marcus Wilhelmsson; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; intercalation; cyanine dye; ruthenium; polarized spectroscopy; threading; groove-binding; kinetics; genetic screening; DNA; fluorescent base analogue;

    Sammanfattning : The work presented in this Thesis focuses on the interaction between nucleic acids and small molecules, as well as binding or incorporation of reporter chromophores into nucleic acids. The results could help in studying and understanding processes that are fundamental to describe mechanisms behind a genetic disorder. LÄS MER

  5. 4. Chiral Ruthenium Dipyrodiphenazine Complexes: DNA Binding and Excited State Relaxation

    Författare :Björn Önfelt; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; polarization spectroscopy; DNA-probe; dppz; excited-state relaxation; intercalation; solvent relaxation; DNA-threading;

    Sammanfattning : Ruthenium complexes with aromatic ligands have been extensively studied due to their interesting photophysical properties, including photophysics and electron transfer upon interaction with nucleic acids. For example, the broad absorption spectrum makes them suitable as antenna molecules in photochemical reaction systems and their ability to accept or donate electrons in their excited state could have potential in opto-electronical devices. LÄS MER

  7. 5. DNA binding properties and femtosecond dynamics of [Ru(phen)₂dppz]²+ systems

    Författare :Björn Önfelt; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; DNA-threading; intercalation; light-switch; linear dichroism; solvent relaxation; absorption anisotropy; polarized light; femtosecond spectroscopy;

    Sammanfattning : .... LÄS MER