Sökning: "therapeutic"

Visar resultat 16 - 20 av 2312 avhandlingar innehållade ordet therapeutic.

1. 16. Development of electrochemical sensor and biosensor platforms : detection of therapeutic drugs and heavy metal ions

   Författare :Sereilakhena Phal; Solomon Tesfalidet; Britta Lindholm-Sethson; William Siljebo; Pankaj Vadgama; Umeå universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Sensors; electrode surface modification; electrochemical immitance spectroscopy; square wave anodic stripping voltammetry; singular value decomposition; therapeutic drugs; heavy metals;

   Sammanfattning : Electrochemical sensors and biosensors combine the sensitivity of electroanalytical methods with the selectivity of a sensor or biosensor surface. The chemical or biochemical component (receptor) in the sensor recognizes an analyte and produces an electrical signal which is proportional to the analyte concentration. LÄS MER

3. 17. Compact-disc microfluidic methods for characterization of therapeutic antibodies : Analysis of post-translational modifications

   Författare :Thi Thuy Tran; Gunnar Thorsén; McLean John; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Microfluidic CD; therapeutic antibodies; post-translational modifications; glycosylation profiling; multivariate statistical analysis; MALDI-MS; Analytical Chemistry; analytisk kemi;

   Sammanfattning : Characterization of post-translational modifications (PTMs) of therapeutic proteins is very important during the bioprocess development to maintain desired product quality and during the submission process to regulatory authorities for product approval. Monitoring glycosylation in pharmacokinetic studies can be useful to evaluate the dependence of clearance rates on different glycoforms. LÄS MER

4. 18. Deciphering Binding Patterns of Therapeutic Antibodies with Immune Cells : From Method Development to Application

   Författare :Sina Bondza; Jos Buijs; Marika Nestor; Mark Cragg; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; affinity; binding kinetics; CD20; cell-based assay; immunology; receptor-ligand interaction; therapeutic antibody; Immunologi; Immunology; Medical Cell Biology; Medicinsk cellbiologi;

   Sammanfattning : Reversible binding, for example between signaling molecules and receptors on the cell surface, is one of the main means to communicate information in cellular systems. Knowledge about how molecules interact is crucial for both understanding biological function and for therapeutic intervention. LÄS MER

5. 19. Möten i psykodynamisk barnpsykoterapi : Förväntningar, samspel och förändring

   Författare :Fredrik Odhammar; Max Scheja; Gunnar Carlberg; Sonja Olin Lauritzen; Björn Wrangsjö; Stockholms universitet; []
   Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Child psychotherapy; expectations; therapeutic alliance; common factors; psychotherapy process; outcome; case study; treatment goals; intersubjectivity; mixed-methods; pedagogik; Education;

   Sammanfattning : This thesis aims to increase the knowledge of courses and processes of change prior to and during psychodynamic child psychotherapy with parallel parent contact. The dissertation examines parents’ and psychotherapists’ stated goals and expectations prior to the child’s psychotherapy, processes of change focusing on the psychotherapeutic encounter between child and psychotherapist, and outcome gauged by standardized measures compared to experienced change regarding the child’s problems. LÄS MER

7. 20. The role of the thromboinflammatory response under hemolytic conditions : pathophysiological mechanisms and therapeutic inhibition

   Författare :Alexandra Gerogianni; Per H. Nilsson; Camilla Mohlin; Tom Eirik Mollnes; Kristina Nilsson Ekdahl; Mihály Józsi; Linnéuniversitetet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Hemolysis; heme; thromboinflammation; biomaterials; complement inhibition; LVAD; IONPs; Biomedical Sciences; Biomedicinsk vetenskap; Immunologi; Immunology;

   Sammanfattning : In blood circulation, the complement and the coagulation cascades, together with platelets and endothelial cells form a complex network of crosstalk. When dysregulated, these interactions can lead to inflammation in combination with thrombosis (thromboinflammation) and the manifestation of pathophysiological complications. LÄS MER