Sökning: "therapeutic drugs"

Visar resultat 1 - 5 av 403 avhandlingar innehållade orden therapeutic drugs.

  1. 1. Development of electrochemical sensor and biosensor platforms : detection of therapeutic drugs and heavy metal ions

    Författare :Sereilakhena Phal; Solomon Tesfalidet; Britta Lindholm-Sethson; William Siljebo; Pankaj Vadgama; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Sensors; electrode surface modification; electrochemical immitance spectroscopy; square wave anodic stripping voltammetry; singular value decomposition; therapeutic drugs; heavy metals;

    Sammanfattning : Electrochemical sensors and biosensors combine the sensitivity of electroanalytical methods with the selectivity of a sensor or biosensor surface. The chemical or biochemical component (receptor) in the sensor recognizes an analyte and produces an electrical signal which is proportional to the analyte concentration. LÄS MER

  3. 2. Theorizing the therapeutic process in substance use-related dependency treatment

    Författare :Therese von Braun; Sam Larsson; Yvonne Sjöblom; Inga Tidefors; Stockholms universitet; []
    Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Therapeutic process; therapeutic relationship; therapeutic alliance; substance use-related dependency; treatment; self; self-theoretical perspective; self-theory; alcoholic self; drug self; sober self; mind; multi-mind; multidimensional model; Social Work; socialt arbete;

    Sammanfattning : The aim of the thesis was to increase knowledge on how to understand the therapeutic process highlighting the importance of the therapeutic relationship as described by therapists and clients in substance use-related dependency treatment. The research questions were related to how the therapeutic process can contribute to a positive outcome considering the therapists’, the clients’ and close co-dependent relatives’ perspectives. LÄS MER

  4. 3. Enhancing the therapeutic effect of biological drugs with protein engineering : Focusing on pre-clinical Alzheimer’s disease therapy

    Författare :Fadi Rofo; Greta Hultqvist; Stina Syvänen; Sara Mangsbo; Joy Zuchero; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Alzheimer’s disease; amyloid-beta; blood-brain barrier; transferrin receptor; protein-drugs; multivalent-bispecific antibodies;

    Sammanfattning : Aggregation of the amyloid-β peptide (Aβ) is one of the main pathological hallmarks in Alzheimer’s disease (AD). The soluble Aβ aggregates (oligomers and protofibrils) have shown to be the most harmful species. Hence, targeting these aggregates can be of therapeutic potential. LÄS MER

  5. 4. Bioanalytical development for application in therapeutic drug monitoring : focus on drugs used in psychiatry

    Författare :Daniel Öhman; Olof Beck; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : Introduction: Since the 1950s and onwards, many new psychoactive drugs have been successfully introduced in clinical practice. A common feature of these drugs is a profound metabolism before clearance from the body. LÄS MER

  7. 5. Pharmacokinetics of antidepressant drugs : naturalistic and clinical trials

    Författare :Margareta Reis; Finn Bengtsson; Edoardo Spina; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : Depression is a major public health problem and it is predicted to be the second leading cause of disease burden by the year 2020. The pharmacological treatment period for major depressive disorder (MDD) is relatively long and sometimes prophylactic over many years. LÄS MER