Sökning: "therapeutic drug monitoring"
Visar resultat 11 - 15 av 66 avhandlingar innehållade orden therapeutic drug monitoring.
11. Pharmacometric Approaches to Improve Dose Individualization Methods in Hemophilia A
Sammanfattning : Hemophilia A is a bleeding disorder caused by the lack of functional coagulation factor VIII (FVIII). The overall aim of this thesis was to improve dose individualization of FVIII replacement therapy in hemophilia A using pharmacometric approaches. LÄS MER
12. Monitoring anti-infectives and antibiotic resistance genes : with focus on analytical method development, effects of antibiotics and national perspectives
Sammanfattning : Antibiotics are biologically active and are globally used in humans and animal medicine for treatment and in sub-therapeutic amounts as growth promoters in animal husbandry, aquaculture and agriculture. After excretion, inappropriate disposal and discharge from drug production facilities they enter into water bodies either as intact drugs, metabolites or transformed products. LÄS MER
13. Drug utilization 90% : using aggregate drug statistics for the quality assessment of prescribing
Sammanfattning : Introduction: There is room for improvement in prescribing. Although a range of indicators have been developed to assess the quality of prescribing, none of them focus on all drugs and there is a gap between what is credible for health care professionals and what can be achieved with the readily available data. LÄS MER
14. Possibilities of dried blood spots as a matrix in therapeutic drug monitoring of antiepileptic drugs in children
Sammanfattning : For children with epilepsy, therapeutic drug monitoring (TDM) of antiepileptic drugs (AEDs) is essential for treatment. TDM monitoring requires two visits to a health care unit, first for collection of the blood sample before the morning dose and a few days later the family will travel once again to see the pediatrician. LÄS MER
15. Capacitive Biosensor - A Tool for Ultrasensitive Analysis : Application in Clinical Analysis and Process Monitoring
Sammanfattning : Increasing demands for highly sensitive, accurate, fast and portable analytical assays have led to the development of new analytical tools. The integration of highly specific biological sensing elements and appropriate transducers has enabled design of even more efficient biosensor devices for the detection of target substances. LÄS MER