Sökning: "the nucleus of the solitary tract"

Visar resultat 1 - 5 av 15 avhandlingar innehållade orden the nucleus of the solitary tract.

  1. 1. Taste Hedonics and the Intake of Alcohol and Food

    Författare :Anna Söderpalm; Göteborgs universitet; []
    Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Alcohol drinking; Adrenalectomy; Corticosterone; Cyanoketone; Food intake; Food restriction; GABA; Metyrapone; Taste reactivity; Benzodiazepine; Chlordiazepoxide; Cis Z -flupentixol; Diazepam; Flumazenil; Microinjections; Midazolam; Nucleus of the Solitary tract; Palatability; Parabrachial nucleus; Peduculopontine Tegmental Nucleus; Reward; 4th ventricle.;

    Sammanfattning : This thesis includes four papers based on animal experimental work. They analyze the way in which activation of a specific motivational state - hunger- modulates the rewarding actions of alcohol and taste palatability. LÄS MER

  3. 2. Studies of cytokine mediated regulation of central nervous functions : role of prostaglandins

    Författare :Monica Ek; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :interleukin-1; prostaglandin E2; central nervous system; HPA axis; fever; vagus nerve;

    Sammanfattning : The communication between the immune system and the central nervous system (CNS) results in an array of centrally regulated illness responses, including fever and increased hypothalamus-pituitary-adrenal (HPA) axis activity. The mechanisms by which the immune system signals the brain across the blood-brain barrier have not been completely elucidated, but proinflammatory cytokines, like interleukin-1 (IL-1), are believed to act as important mediators. LÄS MER

  4. 3. Structure and expression of the TP and EP1 prostanoid receptor genes

    Författare :Björn Båtshake; Institutionen för experimentell medicinsk vetenskap; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neuropsykologi; Neurologi; neurofysiologi; Neurology; neuropsychology; neurophysiology;

    Sammanfattning : Prostanoids are ubiquitously distributed lipid signaling molecules derived from arachidonic acid, that exhibit numerous and diverse biological effects in a variety of physiological and pathophysiological conditions. The cell surface receptors for the prostanoids belong to the family of G protein-coupled receptors. LÄS MER

  5. 4. IL-6 and GLP-1 in body fat regulating parts of the CNS in healthy mice

    Författare :Fredrik Anesten; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; IL-6; IL-6Rα; GLP-1; obesity; hypothalamus; brainstem; tanycytes; immunohistochemistry;

    Sammanfattning : It has previously been shown that mice lacking interleukin-6 (IL-6) develop mature onset obesity. The weight-suppressing effects of IL-6 have been assumed to be exerted at a central level, as supported by the fact that ICV- injections, but not peripheral injections of IL-6, increases energy expenditure and decreases body fat in rodents. LÄS MER

  7. 5. Role of corticotropin-releasing factor, somatostatin and leptin in vagal nerve function and control of gastric emptying

    Författare :Ulrika Smedh; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The overall aim of this thesis was to study the effects of centrally acting CRF and leptin, and peripherally acting somatostatin on gastric emptying of glucose. Freely moving rats bearing chronic intragastric fistulas received intragastric infusions (1.0 ml/min) of glucose (12.5 % or 25 %) during 6-18 min. LÄS MER