Sökning: "the estrogen receptor"

Visar resultat 21 - 25 av 267 avhandlingar innehållade orden the estrogen receptor.

1. 21. Studies of hyperandrogenicity and the metabolic syndrome in premenopausal women

   Författare :Fariba Baghaei; Göteborgs universitet; []
   Nyckelord :androgens; SHBG; HPA axis; abdominal obesity; insulin; HDL; metabolic syndrome; ovarian volume; PCOS; polymorphism; genetics; androgen receptor; estrogen receptor; aromatase;

   Sammanfattning : An androgenic sex hormone profile appears to be a typical feature of the metabolic syndrome (MetS) and a powerful risk factor for the development of type 2 diabetes in women. The causes of relative hyperandrogenicity (HA) are not clearly defined. LÄS MER

3. 22. The estrogen receptor in fish and effects of synthetic estrogens in the environment - Ecological and evolutionary perspectives and societal awareness

   Författare :Lina Nikoleris; Biodiversitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; the estrogen receptor; salmon evolution and ecology; contraceptives; information gaps; synthetic hormones; EE2; Atlantic salmon Salmo salar ; brown trout Salmo trutta ; roach Rutilus rutilus ;

   Sammanfattning : Synthetic hormones are a group of pharmaceuticals used for various human and animal treatments. However, consumption and disposal of these substances have also given rise to negative effects and environmental problems for organisms in the wild which is why these substances have been classified as estrogenic endocrine-disrupting chemicals (EDCs). LÄS MER

4. 23. Steroid-Metabolizing Cytochrome P450 (CYP) Enzymes in the Maintenance of Cholesterol and Sex Hormone Levels

   Författare :Hanna Pettersson; Maria Norlin; Kjell Wikvall; Paolo Parini; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; CYP27A1; CYP7B1; cytochrome P450; estrogen receptor; androgen receptor; cholesterol; sex hormone; hydroxylation; steroid metabolism; regulation of steroid levels; Pharmaceutical biochemistry; Farmaceutisk biokemi; Farmaceutisk biokemi; Pharmaceutical Biochemistry;

   Sammanfattning : The enzymes CYP27A1 and CYP7B1 are widely expressed in various human tissues and perform catalytic reactions in cholesterol homeostasis and endocrine signaling. We have investigated the metabolism of a synthetic oxysterol. LÄS MER

5. 24. Folate - Associations with breast cancer depending on intake, metabolism, genetic variation and estrogen receptor status

   Författare :Ulrika Ericson; Diabetes - kardiovaskulär sjukdom; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; folate; B-vitamins; breast cancer; diet; epidemiology; nutrition; plasma; polymorphism; estrogen receptor α; estrogen receptor β; reproducibility; prospective;

   Sammanfattning : Folate is a B-vitamin that may influence cancer development via its role as methyl donor for DNA synthesis and methylation. Plant foods contain many bioactive compounds including folate and fiber. Results from the Malmö Diet and Cancer (MDC) cohort indicate lower breast cancer risk at high fiber intake. LÄS MER

7. 25. Biomarkers in non-small cell lung carcinoma : methodological aspects and influence of gender, histology and smoking habits on estrogen receptor and epidermal growth factor family receptor signalling

   Författare :Christina Karlsson; Karin Piehl-Aulin; Ulf Tidefelt; Gisela Helenius; Leif Johansson; Örebro universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Non-small cell lung carcinoma; estrogen receptor; epidermal growth factor receptor; HER-4; tissue microarray; immunohistochemistry; smoking habits; in situ hybridisation; Onkologi; Oncology;

   Sammanfattning : Non-small cell lung carcinoma is a leading cause of cancer mortality worldwide. There are gender and smoking associated differences both in tumour types and clinical outcome. Squamous cell carcinomas (SCC) are more frequent among smoking men while females develop adenocarcinomas (ADCA). LÄS MER