Sökning: "tetracycline-regulated gene expression"

Hittade 4 avhandlingar innehållade orden tetracycline-regulated gene expression.

  1. 1. Molecular Mechanisms in Endothelial Cell Differentiation

    Författare :Emma Rennel; Pär Gerwins; Lena Claesson-Welsh; Ian Zachary; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pathology; angiogenesis; FGF-2; VEGF-A; signal transduction; in vitro angiogenesis assay; immortalized brain endothelial cells; H-Ras; tetracycline-regulated gene expression; microarray; telomerase immortalized human microvascular endothelial cells; differentiation; Patologi; Pathology; Patologi;

    Sammanfattning : Angiogenesis is the formation of new blood vessels from the pre-existing blood vessels. Blood vessels are composed of endothelial cells and supporting musculature. Angiogenesis is regulated by numerous soluble ligands and by cell-matrix interactions. LÄS MER

  3. 2. Adenovirus vector systems permitting regulated protein expression and their use for in vivo splicing studies

    Författare :Magnus Molin; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; Adenovirus; vector; inducible; gene expression; ASF SF2; splicing; Biokemi; Biochemistry; Biokemi; Medical Virology; medicinsk virologi;

    Sammanfattning : We have constructed two adenovirus-based gene expression vector systems permitting regulated protein expression. They are based on the tetracycline-regulated Tet-ON- and the progesterone antagonist RU 486-regulated gene expression systems, which were rescued into E1-deficient adenovirus vectors. LÄS MER

  4. 3. Construction of Adenovirus Vectors for Studies of Protein Function and RNA Interference

    Författare :Saideh Berenjian; Göran Akusjärvi; Mikael Berg; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Microbiology; Adenovirus; viral vectors; VA RNAI II; RNAi; Tet-ON OFF; RNA splicing; Mikrobiologi; Microbiology; Mikrobiologi;

    Sammanfattning : During an adenovirus infection the accumulation of alternatively spliced mRNAs is subjected to a tight temporal regulation. The IIIa protein is a structural protein expressed exclusively late after infection. LÄS MER

  5. 4. Inhibition of apoptosis by the Us3 protein kinase of herpes simplex virus 1

    Författare :Anna Cartier; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Us3; unique short 3; HSV; herpes simplex virus; NK; natural killer; LAK; lymphokine activated killer; MHC; major histocompatibility complex;

    Sammanfattning : The Herpes Simplex Virus 1 (HSV-1) US3 protein kinase is part of the anti-apoptotic arsenal that salvage HSV-1-infected cells from damage caused by different stimuli. The Us3 gene encodes a protein kinase that phosphorylates serine/threonine residues within a specific arginine-rich consensus sequence. LÄS MER