Sökning: "tet genes"

Visar resultat 1 - 5 av 8 avhandlingar innehållade orden tet genes.

  1. 1. Evolution and Mechanisms of Tigecycline Resistance in Escherichia coli

    Författare :Marius Linkevičius; Dan I. Andersson; Linus Sandegren; Patrice Courvalin; Uppsala universitet; []
    Nyckelord :Tigecycline; Bacterial resistance; Fitness; Escherichia coli; AcrAB; LPS; Tet proteins; Tet A ; Tet K ; Tet M ; Tet X ; tet genes; pUUH239.2; Mikrobiologi; Microbiology;

    Sammanfattning : Antibiotic resistance is an ongoing global medical crisis and we are in great need of new antibacterial agents to combat rapidly emerging resistant pathogens. Tigecycline is one of few drugs that have been introduced into medicine during the last two decades. LÄS MER

  3. 2. Hox transcription factors in hematopoiesis

    Författare :Jon Mar Björnsson; Avdelningen för molekylärmedicin och genterapi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; extracellular fluids; Hematologi; extracellulära vätskor; Haematology; hematopoies; tet; Hox; cre lox;

    Sammanfattning : Hematopoiesis is a lifelong, dynamic process in which a small number of pluripotent hematopoietic stem cells (HSC) residing in the bone marrow (BM) give rise to billions of mature blood cells of both myeloid and lymphoid origin each day. This enormous capacity of HSC has been utilized in BM transplantations for 4 decades and is also very important for future gene therapy. LÄS MER

  4. 3. Antibiotic resistance in Lactobacillus reuteri and Lactobacillus plantarum

    Författare :Maria Egervärn; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : Lactic acid bacteria (LAB) may act as reservoirs of antibiotic resistance genes that can be transferred via the food chain or within the gastrointestinal tract to pathogenic bacteria. This thesis provides data required for assessing the potential risk of using antibiotic resistant strains of the LAB species Lactobacillus reuteri and Lactobacillus plantarum as food processing aids or probiotics. LÄS MER

  5. 4. Promoter Engineering for Cyanobacteria : An Essential Step

    Författare :Hsin-Ho Huang; Peter Lindblad; James Golden; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; synthetic biology; cyanobacteria; promoter; engineering; TetR; DNA breathing dynamics; transcription; regulation;

    Sammanfattning : Synthetic biology views a complex biological system as an ensemble in the hierarchy of parts, devices, systems, and networks. The practice of using engineering rules such as decoupling and standardization to understand, predict, and re-build novel biological functions from model-driven designed genetic circuits is emphasized. LÄS MER

  7. 5. A multi-omics approach to reveal critical mechanisms of activator protein 1 (AP-1) in cancer

    Författare :Dandan Song; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Activator protein-1 (AP-1) is a transcriptional factor complex that mainly consists of Fos and Jun family members. Jun proteins can form both homodimers and heterodimers, whereas Fos family members only form heterodimers with the Jun family. Fra-1 is a member of the Fos family proteins and plays a vital role in breast cancer progression. LÄS MER