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  1. 1. Testosterone, 17β-estradiol and pubertal growth

    Författare :Anna-Karin Albin; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; testosterone; estrogen; pubertal growth; growth hormone treatment;

    Sammanfattning : Background and aims: It is well established that the interaction of sex steroids with the growth hormone (GH)/ insulin-like growth factor 1 (IGF-1) axis is of major importance in children for normal pubertal growth. However, detailed understanding is still lacking. LÄS MER

  2. 2. Anabolic Androgenic Steroids : Neurobiological Effects of Nandrolone, Testosterone, Trenbolone, and Stanozolol

    Författare :Sofia Zelleroth; Mathias Hallberg; Astrid Bjørnebekk; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Anabolic androgenic steroids; testosterone; nandrolone; trenbolone; stanozolol; central nervous system; primary cortical cell cultures; rats; multivariate concentric square field; novel object recognition.; Farmaceutisk vetenskap; Pharmaceutical Science;

    Sammanfattning : The use of anabolic androgenic steroids (AAS) for recreational purposes is a health concern, as long-term AAS-use in supraphysiological doses is associated with severe physical and psychological adverse effects. Several behavioral and cognitive problems are reported after long-term AAS-use, and alterations in brain morphology as well as neurotransmitter systems have been reported. LÄS MER

  3. 3. Testosterone and 17beta-oestradiol secretions in children and adolescents. Assay development, levels for comparison and clinical applications

    Författare :Carina Ankarberg-Lindgren; Göteborgs universitet; []
    Nyckelord :17beta-oestradiol; testosterone; sensitive assay; data for comparison; prepuberty; puberty; children; pubertal induction.;

    Sammanfattning : Accurate measurements of 17beta-oestradiol and testosterone are important in clinical settings of pubertal disorders and hormone replacement therapy among children. Most assays for measurement of these steroids are optimised for fertility investigations in adults and are not sensitive enough for quantification in children. LÄS MER

  4. 4. Testosterone Use and Abuse : Methodological Aspects in Forensic Toxicology and Clinical Diagnostics

    Författare :Yvonne Lood; Jeanette Wahlberg; Johan Ahlner; Bertil Ekman; Elisabeth Aardal; Martin Josefsson; Ingemar Thiblin; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Abuse of anabolic androgenic steroids (AAS) is widespread in society and is today a major public health problem, associated with mental and somatic adverse effects and risk behavior, such as use of other illicit drugs and criminality. Testosterone, the most important endogenous male androgen, is therapeutically used in replacement therapy but is also extensively used as a doping agent. LÄS MER

  5. 5. Testosterone Analysis in Hair

    Författare :Julia Preinbergs; Jakob Ström; Elvar Theodorsson; Edvin Ingberg; Ulrik Kvist; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : The effects of testosterone in the body are dependent on the concentrations at the target organs, as well as the susceptibility of the androgen receptor. Steroid hormones circulate in the bloodstream bound to proteins, and only a small part is unbound and free to exert its effect at the receptors. LÄS MER