Sökning: "tendon cell"
Visar resultat 11 - 15 av 25 avhandlingar innehållade orden tendon cell.
11. Chondrocyte-matrix interactions: with emphasis on the collagen binding integrin a10ß1
Sammanfattning : The work in this thesis has been focused on chondrocyte integrins and their interaction with the matrix proteins chondroadherin (CHAD) and collagen type II (CII). Affinity purification of CHAD-binding proteins from chondrocyte lysate, followed by immunoprecipitation of EDTA-eluted material identified alpha2beta1 as a CHAD-binding integrin. LÄS MER
12. Inflammation and tendon healing
Sammanfattning : Tendons heal through three different overlapping phases; the inflammatory, proliferative and remodeling phase. Many studies have investigated what factors influence healing of tendons. However, little was known about inflammation and the immune cells present during Achilles tendon healing by the time this thesis started. LÄS MER
13. Synchrotron-based characterization of mechanobiological effects on the nanoscale in musculoskeletal tissues
Sammanfattning : Collagen is the main organic building block of musculoskeletal tissues. Despite collagen being their smallest load bearing unit, these tissues differ significantly in mechanical function and properties. A major factor behind these differences is their hierarchical organization, from the collagen molecule up to the organ scale. LÄS MER
14. Computational modeling of mechanobiology in intact and healing rat Achilles tendon
Sammanfattning : Tendons fulfill an important musculoskeletal function by enabling energy-efficient force transmission between muscles and bones. The tendon is a collagen-rich connective tissue that adapts to mechanical loading through mechanobiological processes. LÄS MER
15. BMP treatment for improving tendon repair. Studies on rat and rabbit Achilles tendons
Sammanfattning : We wanted to improve tendon healing by adding a growth factor. Bone Morphogenetic Proteins (BMPs) are well known to stimulate bone healing and bone formation. The local environment is of major importance for cell differentiation after a BMP has been added. LÄS MER