Sökning: "telencephalon"

Visar resultat 11 - 15 av 18 avhandlingar innehållade ordet telencephalon.

  1. 11. On molecular mechanisms of neural differentiation and forebrain development

    Författare :Erik Södersten; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Telencephalic development is an extraordinary complex process where neural structures of highly diverse cell compositions emerge as the result of multiple developmental strategies imposing tight regulation, balance and timing of gene expression. Embryonic telencephalic neural stem cells (NSCs) can form the major cell types found in the telencephalon, and are thus an excellent model for studying transcriptional control of lineage choice mechanisms in CNS development. LÄS MER

  3. 12. Of mice and men : SOD1 associated human amyotrophic lateral sclerosis and transgenic mouse models

    Författare :Karin Sixtensdotter Graffmo; Thomas Brännström; Stefan Marklund; Elisabeth Englund; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; aggregates; ALS; amyotrophic lateral sclerosis; inclusions; misfolded; vacuolisation; SOD1; transgenic; Pathology; Patologi;

    Sammanfattning : Amyotrophic lateral sclerosis, ALS, is a progressive fatal neurodegenerative disorder affecting motor neurones in motor cortex, brain stem and spinal cord. This inevitably leads to paralysis, respiratory failure and death. LÄS MER

  4. 13. Early domestication? : Phenotypic alterations of Red Junglefowl selected for divergent fear of humans

    Författare :Beatrix Agnvall; Per Jensen; Hannah Rowland; Linköpings universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : Domestication is the process through which animals adapt to conditions provided by humans. The domesticated phenotype differs from wild ancestors in a number of traits relating to physiology, morphology and behaviour. LÄS MER

  5. 14. From stem cells to neurons : a BMPy ride

    Författare :Therese Andersson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Pinpointing the mechanisms behind the formation of the vertebrate development has been an intriguing and challenging task for researchers for several decades. In the 1980s two independent groups managed to isolate cells from the inner cell mass of a mouse blastocyst and to culture and expand them in vitro, while maintaining their pluripotency. LÄS MER

  7. 15. Electrophysiological and molecular diversity of forebrain interneurons

    Författare :Carolina Bengtsson Gonzales; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Despite their low abundance, telencephalic interneurons demonstrate a great amount of molecular and electrophysiological heterogeneity, suggesting that they exhibit different functions within the circuit. Interneurons are commonly classified into distinct cell types based on their morphology, intrinsic electrophysiological properties, connectivity or molecular profile. LÄS MER