Sökning: "targeted therapy"
Visar resultat 11 - 15 av 323 avhandlingar innehållade orden targeted therapy.
11. Novel experimental targeted therapy of neuroblastoma
Sammanfattning : Neuroblastoma, a malignancy of the sympathetic nervous system, is the most common solid extracranial tumor of infancy and is responsible for around 15% of the cancer-related deaths in children. For the entire group the survival has increased over the last decades, but despite today's intense muti-modal therapy the survival of high-risk neuroblastomas lies just around 50%. LÄS MER
12. Targeted therapy in chronic lymphocytic leukemia
Sammanfattning : Chronic lymphocytic leukemia (CLL) is characterized by the accumulation of mature B lymphocytes in blood, bone marrow and lymphoid tissues. Historically, patients with TP53 aberration and with refractoriness to chemoimmunotherapy had a dismal prognosis. LÄS MER
13. Gene Therapy for Neurological Disorders
Sammanfattning : Gene therapy is an attractive strategy for neurological disorders, such as Parkinson’s disease and epilepsy, for several reasons. Introduction of genes with a therapeutic potential can be achieved locally, by accurate injections in the compromised tissue, and release of a transgene therapeutic substance can be regulated by the surrounding host neural circuitry. LÄS MER
14. Cancer and Therapy: A look into stemness and the tumour microenvironment
Sammanfattning : Therapy is the often-used treatment for cancer patients, even those that undergo resection surgery. While milestones have been surpassed throughout the decades for a number of cancer types, there are those that comprise of characteristics limiting effectiveness of treatments. LÄS MER
15. On severe traumatic brain injury : aspects of an intra cranial pressure-targeted therapy based on the Lund concept
Sammanfattning : Severe Traumatic Brain Injury (sTBI) is a major cause of mortality and morbidity. At the Department of Neurosurgery Umeå University Hospital subjects with sTBI are treated with an intracranial pressure (ICP) guided therapy based on physiological principles, aiming to optimise the microcirculation of the brain so avoiding secondary brain injuries. LÄS MER
