Sökning: "tailored chemotherapy"

Visar resultat 6 - 10 av 15 avhandlingar innehållade orden tailored chemotherapy.

  1. 6. Clinical significance of immunohistochemistry in breast cancer diagnostics

    Författare :Slavica Janeva; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; breast cancer biomarkers; immunohistochemistry; surrogate subtype; RT- qPCR; multifocal breast cancer; lymph node metastasis; triple-negative breast cancer; older women;

    Sammanfattning : For patients with breast cancer, modern patient-tailored treatment depends on tumor- specific characteristics, i.e., estrogen receptor (ER), progesterone receptor (PR), human epidermal growth factor 2 (HER2), and the proliferation marker Ki67. LÄS MER

  3. 7. Next Generation Sequencing for Measurable Residual Disease Detection in Acute Myeloid Leukemia

    Författare :Erik Delsing Malmberg; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; acute myeloid leukemia; minimal residual disease; massively parallel sequencing; next generation sequencing; NPM1; alloHCT;

    Sammanfattning : Acute myeloid leukemia (AML) is the most common form of acute leukemia and generally associated with a poor prognosis. For both children and adults, the treatment is based on chemotherapy. Allogeneic hematopoietic stem cell transplant (alloHCT) is reserved for patients with intermediate or high risk of relapse, due to its associated risks. LÄS MER

  4. 8. Molecular Signatures of Cancer

    Författare :Esther Edlundh-Rose; Joakim Lundeberg; Peter Södervist; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; : BRAF; NRAS; MGMT; methylation; pyrosequencing; microarray technology; gene expression analysis; Molecular biology; Molekylärbiologi;

    Sammanfattning : Cancer is an important public health concern in the western world, responsible for around 25% of all deaths. Although improvements have been made in the diagnosis of cancer, treatment of disseminated disease is inefficient, highlighting the need for new and improved methods of diagnosis and therapy. LÄS MER

  5. 9. Breast cancer surgery - Aspects of patient-reported outcomes and physical activity

    Författare :Jenny Heiman; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Breast cancer; Surgery; Patient-reported outcomes; Physical activity;

    Sammanfattning : The aim of this thesis was to evaluate patient-reported outcomes (PROs) following breast cancer surgery using three different studies. Paper I examined breast-conserving surgery through an inframammary fold incision using a retrospective cohort (n=27). LÄS MER

  7. 10. Prognostic Factors in Early Stages (FIGO I-II) of Epithelial Ovarian Carcinoma

    Författare :Ingirídur Skírnisdóttir; Seija Grenman; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Obstetrics and gynaecology; Ovarian cancer; early stages; adjuvant therapy; prognosis; tumor grade; apoptotic regulators; p53; bcl-2; bax; growth factor receptors; HER-2 neu; EGFR; DNA ploidy; Obstetrik och kvinnosjukdomar; Obstetrics and women s diseases; Obstetrik och kvinnosjukdomar; Obstetrics and Gynaecology; obstetrik och gynekologi;

    Sammanfattning : From January, 1988, to December, 1993, 113 patients with FIGO stage IA-IIC epithelial ovarian carcinoma were treated with postoperative radiotherapy. The median follow-up period was 74 months. Tumor recurrences were recorded in 33 cases (30%). The cancer-specific survival rate was 72%. LÄS MER