Hittade 3 avhandlingar innehållade ordet tagSNP.
Sammanfattning : The studies in this thesis describe the application of genotyping and allele specific expression analysis to genetic studies. The role of the gene NPC1 in Triglyceride metabolism was explored in mouse models and in humans on the population level in study I. LÄS MER
Sammanfattning : Breast cancer is overall the most common cancer in women worldwide and endometrial cancer is the most common gynaecological cancer in the industrialized world. History of a first-degree relative with breast or endometrial cancer has been related to a twofold increase in risk of the respective diseases. LÄS MER
Sammanfattning : Multiple sclerosis is a chronic neurological disease, where both genetic and environmental factors are influencing the susceptibility and pathogenesis. Epidemiological studies have clearly demonstrated the existence of a genetic component by comparing the degree of shared genetic material and the risk of MS, where the degree of shared genetic material clearly correlates with the risk of MS. LÄS MER