Sökning: "tRNA"
Visar resultat 6 - 10 av 100 avhandlingar innehållade ordet tRNA.
6. tRNA Gene Structures in Bacteria
Sammanfattning : In bacteria, tRNA molecules are produced as precursors with additional nucleotides both upstream and downstream of the tRNA coding sequence. To generate a mature tRNA, the endoribonuclease RNase P removes the upstream sequence, while a number of enzymes can remove the downstream sequence. LÄS MER
7. The ribosome, stringent factor and the bacterial stringent response
Sammanfattning : The stringent response plays a significant role in the survival of bacteria during different environmental conditions. It is activated by the binding of stringent factor (SF) to stalled ribosomes that have an unacylated tRNA in the ribosomal A-site which leads to the synthesis of (p)ppGpp. LÄS MER
8. Functional studies of Escherichia coli stringent response factor RelA
Sammanfattning : RelA is a ribosome associated multi-domain enzyme, which plays a crucial role in adaptation ofEscherichia coli to nutritional stress as such as amino acid deficiency. It detects the deficiency of aminoacids in the cell by monitoring whether a tRNA at the acceptor site (A-site) of the ribosome is chargedwith amino acid or not. LÄS MER
9. Dynamics in Protein Synthesis, Structural Studies of Translation Factors
Sammanfattning : Protein biosynthesis is performed on ribosomes. The ribosome is a complex of ribosomal RNA and proteins forming two subunits. A messenger RNA strand is decoded on the small subunit by charged aminoacyl transfer RNA (aa-tRNA) molecules and each tRNA molecule delivers its amino acid to the growing polypeptide chain on the large subunit. LÄS MER
10. Function of wobble nucleoside modifications in tRNAs of Salmonella enterica Serovar Typhimurium
Sammanfattning : Transfer RNA from all organisms has modified nucleosides and position 34 (the wobble position) is one of the most extensively modified positions. Some wobble nucleoside modifications restrict codon choice (e.g. 5-methylaminomethyl-2-thiouridine, mnm5s2U) while some extend the decoding capacity (e. LÄS MER