Sökning: "systems genetics"
Visar resultat 6 - 10 av 181 avhandlingar innehållade orden systems genetics.
6. Two Optimization Problems in Genetics : Multi-dimensional QTL Analysis and Haplotype Inference
Sammanfattning : The existence of new technologies, implemented in efficient platforms and workflows has made massive genotyping available to all fields of biology and medicine. Genetic analyses are no longer dominated by experimental work in laboratories, but rather the interpretation of the resulting data. LÄS MER
7. Genetic Identification of Corkwing Wrasse Cleaner Fish Escaping from Norwegian Aquaculture
Sammanfattning : The genetic impact of farmed fish escaping aquaculture is a highly debated issue. However, non-target species, such as cleaner fish that are used in fish farms to remove parasitic sea lice, are rarely considered. LÄS MER
8. On Transcriptome Sequencing
Sammanfattning : This thesis is about the use of massive DNA sequencing to investigate the transcriptome. During recent decades, several studies have made it clear that the transcriptome comprises a more complex set of biochemical machinery than was previously believed. LÄS MER
9. Advancing Metabolic Engineering through Combination of Systems Biology and Adaptive Evolution
Sammanfattning : Understanding evolutionary strategies of microorganisms may provide opportunities foradvanced strain development with the aim to produce valuable bio-products from renewablebiomass resources. Through evolutionary processes, microorganisms can attain new traitsassociated with genetic changes that may be useful for the construction of improved strains. LÄS MER
10. Genetics of Two Mendelian Traits and Validation of Induced Pluripotent Stem Cell (iPSC) Technology for Disease Modeling
Sammanfattning : Novel technologies for genome analysis have provided almost unlimited opportunities to uncover structural gene variants behind human disorders. Whole exome sequencing (WES) is especially useful for understanding rare Mendelian conditions, because it reduces the requirements for a priori clinical data, and can be applied on a small number of patients. LÄS MER