Sökning: "systemic"

Visar resultat 1 - 5 av 1629 avhandlingar innehållade ordet systemic.

  1. 1. Systemic sclerosis : vascular, pulmonary and immunological aspects

    Författare :Grethe Neumann Andersen; Solbritt Rantapää Dahlqvist; Lucia Mincheva-Nilsson; Sören Jacobsen; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Systemic sclerosis; interstitial lung disease; MMP-9; Th1 Th2; transcription factors; NO; iNOS; E-selectin; endothelium-dependent dilation; endothelium-independent dilation.; Rheumatology; Reumatologi;

    Sammanfattning : In systemic sclerosis (SSc), interstitial lung disease (ILD) and engagement of the vascular system lead to increased morbidity and mortality. The aim of this thesis was to elucidate, in a consecutively included cohort of SSc (limited and diffuse) patients (n = 33), the T cell cytokine profile driving the disease in ILD and to explore the role of matrix metalloproteinase 9 (MMP-9) and its inhibitor: tissue inhibitor of metalloproteinase 1 (TIMP-1) in the extracellular matrix (ECM) degrading process leading to fibrous scarring and honey combing. LÄS MER

  3. 2. Systemic sclerosis : aspects on pathogenetic mechanisms

    Författare :Rolf Gustafsson; Uppsala universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : .... LÄS MER

  4. 3. A systemic stigmatization of fat people

    Författare :Susanne Brandheim; Clary Krekula; Arja Tyrkkö; Lars-Gunnar Engström; Martin Börjeson; Karlstads universitet; []
    Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; obesity; fatness; systemic; stigmatization; medicalization; transformative; second-order reality; Socialt arbete; Social Work;

    Sammanfattning : The aim of this work was to develop knowledge about and awareness of fatness stigmatization from a systemic perspective. The stigmatization of fat people was located as a social problem in a second-order reality in which human fatness is observed and responded to, in turn providing it with negative meaning. LÄS MER

  5. 4. Towards Systemic Governance of Critical Infrastructure Protection : State and Relevance of a Swedish Case

    Författare :Christine Große; Aron Larsson; Olof Björkqvist; Pär M. Olausson; Alexander Fekete; Mittuniversitetet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Systemic Thinking; Infrastructure; Governance; Critical Infrastructure Protection; Complex Systems; Soft Operations Research; design-oriented Information Systems Research; Integrative System Analysis; KISA; STYREL; Multi-level Planning; Adaption; Emergence; Entropy; Systemic Governance;

    Sammanfattning : The protection of infrastructure that is critical to society’s functionality, survival and progression has gained significance for both national security and research because of its large-scale and interdependent nature. Critical infrastructure can be viewed as a complex, socio-technical system-of-systems that imposes extensive requirements on governance efforts to foster critical infrastructure protection (CIP), regardless of whether it involves public organisations, private organisations or both. LÄS MER

  7. 5. An Information System in its Organisational Contexts : A Systemic Semiotic Longitudinal Case Study

    Författare :Rodney Clarke; Karlstads universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; information systems; longitudinal case study; organisational contexts; organisational semiotics; semiotics; social semiotics; systemic functional linguistics; systemic semiotics; workpractices; Information Systems; Informatik;

    Sammanfattning : This dissertation develops a new form of Systems Analysis based on Systemic Semiotics. Systemic Semiotics, a combination of Social Semiotics and Systemic Functional Linguistic theories, can be used to provide contextual descriptions linking the operations of information systems to their specific situational and organisational contexts. LÄS MER