Sökning: "synthetic biology"
Visar resultat 6 - 10 av 151 avhandlingar innehållade orden synthetic biology.
6. Advancing systems biology of yeast through machine learning and comparative genomics
Sammanfattning : Synthetic biology has played a pivotal role in accomplishing the production of high value commodities, pharmaceuticals, and bulk chemicals. Fueled by the breakthrough of synthetic biology and metabolic engineering, Saccharomyces cerevisiae and various other yeasts (such as Yarrowia lipolytica , Pichia pastoris ) have been proven to be promising microbial cell factories and are frequently used in scientific studies. LÄS MER
7. Chemical biology and digital image processing to unravel complex molecular mechanisms in Arabidopsis
Sammanfattning : The sessile life of plant directed their evolution toward multiple adaptive strategies. Rapid protein turn over has been described to be a key regulatory mechanism for plant adaptation. Ubiquitin-modified proteins are targeted for degradation by the 26S-proteasome. LÄS MER
8. Hybridisation between introduced brown hares and native mountain hares in Sweden
Sammanfattning : To investigate the extent and effect of hybridisation between wild sympatric populations of introduced brown hares (Lepus europaeus) and native mountain hares (L.timidus) in Sweden, the geographic distribution of genetic variation in mitochondrial DNA (mtDNA) and nuclear DNA microsatellite markers were analysed within and between the two species and their presumed hybrids. LÄS MER
9. Structure Function Relationships in Pyrimidine Degrading and Biocatalytic Enzymes, and Their Implications for Cancer Therapy and Green Chemistry
Sammanfattning : This thesis includes the work of two separate projects, studies on pyrimidine degrading enzymes and studies on in vitro evolved enzymes. The common denominator of both projects was the use of structural information to explain functional effects, observed in the studied biocatalysts. LÄS MER
10. Transcriptional and post-transcriptional regulation of vascular smooth muscle cell phenotype - Implications for vascular disease states
Sammanfattning : As the world population is pushing toward 8 billion, cardiovascular diseases (CVD) remain the leading cause of death worldwide, representing 30% of all global deaths. A large body of work has recognized that smooth muscle cells (SMCs) surrounding the blood vessels play a prominent role in the development and progression of cardiovascular diseases. LÄS MER