Sökning: "syngeneic islet transplantation"
Hittade 3 avhandlingar innehållade orden syngeneic islet transplantation.
1. Experimental Studies Aiming to Prevent Type 1 Diabetes Mellitus
Sammanfattning : Type 1 diabetes mellitus (T1DM) is an autoimmune disease in which T-cells and macrophages invade the islets of Langerhans and selectively destroy the insulin producing β-cells, either directly or through the secretion of e.g. cytokines and nitric oxide (NO). This thesis has studied possible strategies to prevent T1DM. LÄS MER
2. Exploration of Conditions Affecting Cytokine Production in Experimental Type 1 Diabetes Mellitus
Sammanfattning : Cytokines are soluble signalling mediators within the immune system, and have been shown to be of importance in the development of type 1 diabetes (T1D). This thesis studied the production of cytokines in experimental models of T1D and during transplantation of insulin-producing islets of Langerhans. LÄS MER
3. Prevention of type 1 diabetes mellitus in experimental studies
Sammanfattning : The aim of the study was to examine the immune response and different immunoprotective strategies in experimental type 1 diabetes mellitus. The autoimmune destruction of the insulin-producing pancreatic β-cells that leads to type 1 diabetes is complex and incompletely understood. LÄS MER