Sökning: "synergistic effect"

Visar resultat 1 - 5 av 232 avhandlingar innehållade orden synergistic effect.

  1. 1. The proteasome as a target for cancer therapy

    Författare :Peter Larsson; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cancer; Cell viability assay; Chemotherapy; Drug repurposing; Genomic and transcriptomic signatures; Prognostic biomarkers; Proteasome; Proteasome genes; Proteasome inhibitors; Drug sensitivity biomarkers; Synergistic effect; Triple-negative breast cancer;

    Sammanfattning : The main objective of this PhD thesis was to evaluate the significance of proteasome genes as prognostic markers for different cancer types and identify specific cancer forms that respond to proteasome inhibition. The proteasome (PSM) plays an important role in maintaining cellular proteostasis and degrades the majority of proteins that require breakdown in the cell. LÄS MER

  3. 2. Oxidation, Creep and Fatigue Synergies in Cast Materials for Exhaust Manifolds

    Författare :Shengmei Xiang; Joakim Odqvist; Baohua Zhu; Stefan Jonsson; Johan Ahlström; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Fatigue; low-cycle fatigue; fatigue in an inert atmosphere; fatigue in a synthetic diesel exhaust atmosphere; corrosion-fatigue; creep-fatigue; high-temperature corrosion; high-temperature fatigue; synergistic effect; corrosion-fatigue synergy; creep-fatigue synergy; high-temperature alloys; fatigue damage; creep-fatigue damage; corrosion-fatigue damage; ductile cast iron; high-alloyed austenitic cast steel; thermal cycling; precipitation; aging.; Teknisk materialvetenskap; Materials Science and Engineering;

    Sammanfattning : The future development of engines of heavy-duty vehicles towards reduced CO2 emission will increase the exhaust gas temperature and render the exhaust atmosphere more corrosive. The current service material of exhaust gas components - a ferritic ductile cast iron called SiMo51 - will soon meet its upper-temperature limit. LÄS MER

  4. 3. Assessment of waters with complex contamination : Effect-based methods for evaluating wastewater treatment requirements and efficiency

    Författare :Veronica Ribé; Åke Forsberg; Monica Odlare; Emma Nehrenheim; Rune Berglind; Magnus Breitholtz; Mälardalens högskola; []
    Nyckelord :Effect-based test methods; wastewater treatment; ecotoxicology; bioassays; Energy- and Environmental Engineering; energi- och miljöteknik;

    Sammanfattning : The access to clean water is one of the prerequisites for a modern, industrialized society. The amount of water withdrawn for human activities has risen exponentially during the last 100 years. This rise in water use is accompanied by the production of vast quantities of contaminated water. LÄS MER

  5. 4. Effects of ionising and non-ionising radiation in cell systems and a rat model for immuno-therapy

    Författare :Catrin Baureus Koch; Neurokirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Kirurgi; ortopedi; traumatologi; Neurology; traumatology; transplantation; Surgery; orthopaedics; cell cultures; abscopal effect; serologi; Immunologi; serology; Immunology; rat tumour model; radiation therapy; radiation sterilisation; pulsed electric fields; interferon-gamma; immuno-gene therapy; neuropsychology; neurophysiology; Neurologi; neuropsykologi; neurofysiologi; glioblastoma multiforme;

    Sammanfattning : The most malignant brain tumour, glioblastoma multiforme (GBM), has an utterly bad prognosis. In spite of all available therapy, the mean survival time is less than a year. In the unique BRIGTT project (Brain Immuno Gene Tumour Therapy), patients at the Dept of Neurosurgery. LÄS MER

  7. 5. Biogas from slaughterhouse waste : Mixtures interactions in co-digestion

    Författare :Jhosané Pagés Diaz; Högskolan i Borås; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Slaughterhouse waste; Agro-Waste; Co-digestion; Synergistic effects; Methanogenic community structure; Resource Recovery; Resursåtervinning;

    Sammanfattning : Global environmental concerns connected to the use of fossil fuels have forced the development ofalternative sustainable energy technologies. The application of anaerobic digestion, from waste streams thatcurrently have no use, can be utilized for bioenergy production. LÄS MER