Sökning: "synemin"

Hittade 4 avhandlingar innehållade ordet synemin.

  1. 1. The muscle cytoskeleton of mice and men : Structural remodelling in desmin myopathies

    Författare :Lena Carlsson; Lars-Eric Thornell; Anders Arnér; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; desmin; nestin; synemin; paranemin; plectin; αB-crystallin; skeletal muscle; heart muscle; myotendinous junction; motor endplate; costamere; anatomi; Human Anatomy;

    Sammanfattning : The muscle fibre cytoskeleton of skeletal and heart muscle cells is composed mainly of intermediate filaments (IFs), that surround the myofibrils and connect the peripheral myofibrils with the sarcolemma and the nuclear membrane. Desmin is the first muscle specific IF protein to be produced in developing muscles and is the main IF protein in mature muscles. LÄS MER

  3. 2. The Role of Reactive Astrocytes in Brain Ischemia and Neurotrauma

    Författare :Lizhen Li; Göteborgs universitet; []
    Nyckelord :astrocytes; intermediate filaments; GFAP; vimentin; reactive gliosis; brain ischemia; neurotrauma;

    Sammanfattning : Astrocytes are the most abundant cell type in the central nervous system (CNS) and increasing evidence now suggests that they play an active role in various brain functions. Astrocytes are involved in the induction and maintenance of the blood brain barrier, as well as the induction and stabilization of neuronal synapses. LÄS MER

  4. 3. Transcriptional control in the vascular wall. Actin-responsive coactivators and smooth muscle transcripts

    Författare :Katarzyna Krawczyk; Cellulär biomekanik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Cardiovascular disease (CVD) is the leading cause of death globally. In the European Union (EU) alone, CVD accounts for 1.8 million deaths each year. CVD is a group of disorders involving the heart and the blood vessels. LÄS MER

  5. 4. Novel markers for smooth muscle cell modulation in vascular injury and disease

    Författare :Urszula Rykaczewska; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Smooth muscle cells (SMCs) are major constituents of the vascular wall, indispensable for basic physiological functions of a healthy vessel, such as regulating vascular tone and blood pressure, but also critical during disease development. With remarkable plasticity, SMCs act as early responders to vessel wall injury, where by activating molecular mechanisms, including phenotypic modulation and transdifferentiation, they counteract detrimental stimuli and aim to restore vascular homeostasis. LÄS MER