Sökning: "synapses"

Visar resultat 6 - 10 av 133 avhandlingar innehållade ordet synapses.

  1. 6. Aspects of memory and representation in cortical computation

    Författare :Martin Rehn; Anders Lansner; Örjan Ekeberg; Peter Földiák; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; cerebral cortex; neural networks; attractor memory; sequence learning; biological vision; generative models; serial order; computational neuroscience; dynamical synapses; Computer science; Datalogi;

    Sammanfattning : Denna avhandling i datalogi föreslår modeller för hur vissa beräkningsmässiga uppgifter kan utföras av hjärnbarken. Utgångspunkten är dels kända fakta om hur en area i hjärnbarken är uppbyggd och fungerar, dels etablerade modellklasser inom beräkningsneurobiologi, såsom attraktorminnen och system för gles kodning. LÄS MER

  2. 7. The interaction between astrocytes and excitatory synapses in health and disease

    Författare :Ipsit Srivastava; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Synaptic transmission forms the basis of neuronal activity and astrocytes play an integral part in this process. Glutamate is the major excitatory neurotransmitter in the brain and an important function of astrocyte during excitatory synaptic activity involves the uptake of glutamate through astrocyte glutamate transporters (EAATs) and hence shaping the excitatory neurotransmission. LÄS MER

  3. 8. Elimination of synapses from injured motoneurons : a model for study of synaptic plasticity in the adult central nervous system

    Författare :Alexander Berg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Synapses are the contacts between nerve cells or between nerve and muscle cells. The integrity of these synapses is crucial for proper function. Several neurodegenerative diseases such as Alzheimer’s disease, multiple sclerosis and neurotrauma involve synaptic pathology. LÄS MER

  4. 9. Effects of influenza A virus infections and interferon-gamma on synapse formation and function in hippocampal neurons in culture

    Författare :Johan Brask; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Influenza A virus; hippocampal neurons; interferon-gamma; electrophysiology; synapses.;

    Sammanfattning : The central nervous system (CNS) can be the target for several infections that include those with RNA viruses. The parenchyma of the CNS is considered an immuneprivileged site since it is protected behind the blood-brain barrier, expresses no or only low levels of major histocompatibility complex (MHC) molecules and contains a paucity of antigenpresenting cells that prime an immune response. LÄS MER

  5. 10. Molecular mechanisms of synaptic transmission and plasticity in spinal sensory pathways

    Författare :Max Larsson; Neurofysiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neurophysiology; neuropsychology; Neurology; electron microscopy; synaptic plasticity; synapse; pain; spinal cord; hyperalgesia; Neurologi; neuropsykologi; neurofysiologi;

    Sammanfattning : An intense, potentially tissue-damaging (noxious) stimulus may lead to enhanced pain sensation of subsequent noxious stimuli (hyperalgesia) and to the perceiving of innocuous stimuli as painful (allodynia). This is thought to result to a large extent from strengthening of synapses established by primary afferent fibers onto spinal cord dorsal horn neurons. LÄS MER