Sökning: "susceptibility"

Visar resultat 11 - 15 av 1284 avhandlingar innehållade ordet susceptibility.

1. 11. Mercury-induced autoimmunity : mechanisms of susceptibility/resistance

   Författare :Hui Hu; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

   Sammanfattning : .... LÄS MER

3. 12. The genetics of systemic lupus erythematosus : Mapping of susceptibility loci for human SLE

   Författare :Anna-Karin B. Lindqvist; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; Systemic lupus erythematosus; complex diseases; genetic susceptibility; linkage analysis; genome scan; candidate gene; Genetik; Clinical genetics; Klinisk genetik; Medical Genetics; medicinsk genetik;

   Sammanfattning : Systemic lupus erythematosus (SLE) is a systemic autoimmune disease affecting organs such as skin, jointsand kidneys. Characteristic for the disease is increased production of autoantibodies, in particular against dsDNA. Previous studies of SLE in mouse models and in humans indicate polygenic inheritance and genetic heterogeneity. LÄS MER

4. 13. Genetic susceptibility to cervical and gastric cancer

   Författare :Patrik Magnusson; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; cervical cancer; gastric cancer; genetic susceptibility; familiality; heritability; HPV; Helicobacter pylori; genetic association; HLA; P53; loss of heterozygosity; Genetik; Clinical genetics; Klinisk genetik; Medical Genetics; medicinsk genetik;

   Sammanfattning : Cervical and gastric cancer both to a large extent depend on infectious agents. Cervical infection with human papilloma virus increases the risk for cervical cancer substantially, and infection with the bacteria Helicobacter pylori increases the risk for gastric cancer. LÄS MER

5. 14. MRI Perfusion Measurements using Magnetic Susceptibility Effects: : Calibration Approaches and Contrast Agent Quantification

   Författare :Emelie Lind; Lund Medicinsk strålningsfysik; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; contrast agent; cerebral blood flow; cerebral blood volume; mean transit time; perfusion; dynamic susceptibility contrast MRI; magnetic susceptibility;

   Sammanfattning : Exchange of oxygen and nutrients between blood and tissue occurs at the capillary level of the blood system. The blood volume flow rate in the capillaries is often referred to as perfusion, and knowledge about perfusion provides important information about the function and viability of the tissue, for example, in patients with ischaemic stroke, cancer, and neurodegenerative diseases. LÄS MER

7. 15. Genetic Mapping of Susceptibility Genes for Systemic Lupus Erythematosus

   Författare :Bo Johanneson; Jean Pierre Hugot; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Molecular genetics; Association analysis; Candidate gene; Complex disease; Genome scan; Linkage analysis; Mapping; Susceptibility genes; Systemic lupus erythematosus; Genetik; Genetics; Genetik; medicinsk genetik; Medical Genetics;

   Sammanfattning : Systemic lupus erythematosus (SLE) is a complex autoimmune disease with unknown etiology. The aim of this thesis was to identify susceptibility regions through genetic mapping, using model-based linkage analysis on nuclear and extended SLE multicase families. LÄS MER